sers – Page 3 – TechConnect Briefs

Rhodamine B Isothiocyanate-Modified Ag Nanoaggregates on Dielectric Beads: A Novel Surface-Enhanced-Raman-Scattering and Fluorescent Imaging Material

Kim K., Lee H.B., Lee J.W., Jang H.J., Lee H.B., Lee J.W., Seoul National University, KR

Ag-deposited silica and polystyrene beads are efficient surface-enhanced-Raman-scattering (SERS) substrates that can be used as core materials of SERS-based biosensors. In this work, we report that once rhodamine B isothiocyanate (RhBITC) is adsorbed onto them, [...]

Silver Particle and Silver Thiolate-Based Molecular Sensing/Recognition Units Operating via Surface-Enhanced Raman Scattering

Kim K., Kim N.H., Park H.K., Kim K., Kim N.H., Lee H.S., Lee Y.M., Lee H.S., Lee Y.M., Seoul National University, KR

Noble metallic nanostructures exhibit a phenomenon known as surface-enhanced Raman scattering (SERS) in which the scattering cross sections are dramatically enhanced for molecules adsorbed thereon. We demonstrate that commercially available Ag(μAg) powders can be used [...]

Utilizing Silver and Gold Nanoparticles for Investigation of Bacterial Cell Wall Biochemical Structure

Culha M., Kahraman M., Yazici M.M., Sahin F., Yeditepe University, TR

Understanding fundamental principles of living systems in their natural environment is always a challenge for scientists. The desire to design and construct novel diagnostic tools makes this understanding a significant prerequisite. Due to its “fingerprinting” [...]

Nanoplex(TM) Biotags: Near-IR Excited, Highly Multiplexed Nanoparticulate Optical Detection Tags for Diagnostic Assays

Penn S., Cromer R., Sha M., Doering B., Brown B., Norton S., Walton I., Oxonica Inc, US

Oxonica Inc has developed a novel optical detection tag for use in point of care diagnostics, cellular imaging assays, and life science assays. Nanoplex(TM) Biotags are silica coated Au nanoparticles that, by virtue of surface [...]

Synthesis, Encapsulation and Functionization of Composite Organic-Inorganic Nanoparticles with Distinctive Surface Enhanced Raman Signatures

Zhang J., Lu Y., Lutz B., Cao M., Qin H., Yamakawa M., Dentinger C., Nguyen L., Chmura A.J., Zhu J., Lutz B., Sung K-B, Swartz K., Wang L., Su X., Sun L., Sung K-B, Berlin A.A., Chan S., Sun L., Sung K-B, Intel Corporation, US

Composite organic-inorganic nanoparticle (COIN) is a new type of optical label for multiplex biomolecule detection. It has strong Raman signal intensity and potentials for a large number of unique Raman signatures. We have developed methods [...]

Silver Nanoparticles for the Simultaneous Raman Detection of Anions, Cations and Neutral Molecules

Sirimuthu N.M.S., Bell S.E.J., Innovative Molecular Materials Group,Queen’s University, UK

Citrate-reduced silver colloids are used extensively for SERS (surface-enhanced Raman spectroscopy) detection of low concentrations of cations but are typically ineffective for detection of anions, since the metal surface bears a negatively charged citrate layer. [...]

Surface Enhanced Raman Scattering by 2D Photonic Crystals: Enhancement and Reproducibility

Netti M.C., Mahnkopf S., Lincoln J.R., Charlton M.D.B., Cox S.J., Ayliffe P., Zoorob M.E., Wilkinson J.S., Baumberg J.J., Perney N.M.B., Jaiswal S.L., Mesophotonics Ltd., UK

Surface Enhanced Raman Scattering (SERS) is a widely utilised technique to enhance the weak Raman spectrum of molecules, enabling detection and identification of ultralow concentrations of particular species. We show both experimentally and theoretically how [...]

Finite-Size Effects and Surface-Enhanced Raman Scattering from Molecules Adsorbed on Noble-Metal Nanoparticles

Pustovit V.N., Walker K.M., Shahbazyan T.V., Jackson State University, US

We study theoretically the role of strong electron confinement on surface-enhanced Raman scattering (SERS) from molecules adsorbed on metal nanoparticles. We describe a novel enhancement mechanism, relevant for nanometer-sized noble-metal particles, which originates from different [...]