RSV – TechConnect Briefs

Gold Nanorods Induce Innate Immune Response and Reduce Respiratory Syncytial Virus Replication

Bawage S., Tiwari P., Singh A., Singh S., Dixit S., Pillai S., Dennis V., Singh A., Singh S., Alabama State University, US

Metallic nanoparticles (MNPs) have been used for diverse applications like sensing molecules, diagnosis of cancer, delivery of drugs and vaccines. Among the various MNPs, the gold nanorods (GNR) have been commonly used for such diagnosis [...]

Peptide RF482 Encapsulated Chitosan – PLGA Nanoparticles Inhibit Respiratory Syncytial Virus

Bawage S.S., Tiwari P.M., Dennis V.A., Singh S.R., Alabama State University, US

Worldwide, human respiratory syncytial virus (RSV) is one of the leading causes of lower respiratory tract infections in children and older adults. Currently, an anti-viral drug ribavirin and RSV neutralizing monoclonal antibody- palivizumab are the [...]

Development of PHEMA-Chitosan nanospheres and encapsulation of RSV-F DNA vaccine

Eroglu E., Waffo A.B., Dennis V.A., Singh S.R., Alabama State University, US

Respiratory Syncytial Virus (RSV) causes serious lower respiratory tract diseases among infants. Unfortunately, no effective vaccine to prevent RSV infection has been developed. RSV fusion gene (RSV-F) is conserved among various strains of RSV. Therefore, [...]

CNT and Silver-CNT Nanoparticles provide immune responses against RSV

Boyoglu C., Boyoglu S., Adiani L., Boyoglu C., Boyoglu S., Mishra M., Rangari V., Dennis V., Singh S.R., Alabama State University, US

Nanobiotechnology and its potential to be used in treating and diagnosing general and viral infections have allowed us to step into a new realm, when dealing with Respiratory synctical virus (RSV). RSV has long been [...]

Respiratory Syncytial Virus Inhibition by Gold and Titanium Nanoparticles

Vig K., Boyoglu S., Rangari V., Pillai S., Singh S.R., Alabama State University, US

Respiratory Syncytial Virus (RSV) is the leading cause of severe respiratory illnesses including bronchiolitis and pneumonia in young children. The RSV surface proteins F (fusion) and G (attachment) are major targets for vaccine development against [...]

Use of Nanoparticles as Therapy for Respiratory Syncytial Virus Inhibition

Vig K., Boyoglu S., Rangari V., Sun L., Singh A., Singh S.R., Pillai S., Singh A., Singh S.R., Alabama State University, US

Respiratory Syncytial Virus is the leading cause of severe respiratory illnesses such as bronchiolitis and pneumonia in young children. RSV is a paramyxovirus with negative-sense genomic RNA that encodes for eleven proteins, two of which, [...]