reactive oxygen species – TechConnect Briefs

Mitochondria-targeting Gold Nanoparticles for Improved Therapeutic Efficacy of Photodynamic Therapy of Breast Cancer

Yang Y., Gao N., Hu Y., Jia C., Du H., Wang H., Stevens Institute of Technology, US

Photodynamic therapy (PDT) is an emerging minimally invasive therapeutic modality for a variety of oncologic diseases. In recognition of their superior optical and surface plasmonic properties, gold nanoparticles (Au NPs) can be utilized as the [...]

Co0.5Fe2.5O4 nanoparticle biological impact – comparative study on environmental cellulolytic fungi

Oprica L., Andries M., Nadejde C., Creanga D., Alexandru Ioan Cuza University, RO

Cobalt ferrite magnetic nanoparticles (MNPs) were prepared by co-precipitation being further electrostatically stabilized in solution (particularly used in experimental cancer treatment through hyperthermia). We focused on the biological impact of MNPs following their release in [...]

The scavenging of reactive oxygen species and the potential for cell protection by fullerenols with different isoelectric points

Li J., Liu X., He R., Chang Y., Zhang M., Liu X., Jin J., Sun B., Zhao Y., Xing G., Chinese Academy of Sciences, CN

Fullerenols were known as the major water-soluble derivatives of fullerene that possess particular signiﬁcance biological effects such as anticancer active and free radical scavengers. We have reported a novel method for purifying nanoparticles of fullerenols, [...]

Indium Phosphide : Cadmium Free Quantum Dots for Cancer Imaging and Therapy

Chibli H., Carlini L., Park S., Dimitrijevic N., Nadeau J.L., McGill University, CA

We synthesised Indium phosphide (InP) quantum dots (QDs) with different shell layer. We demonstrate highly fluorescent labeling of cell lines after nonspecific endocytosis of the QD. With spin-trap electron paramagnetic resonance (EPR) spectroscopy and reporter [...]