protein microarray – TechConnect Briefs

Optimizing antibody microarrays for high resolution SPR microscopy

Kim G., Nishimoto A., Cong S., Johnson E., Guan H.W., Petcavish B., Lasky S., Hood L., Campbell C.T., Lumera Corporation, US

A high resolution surface plasmon resonance (SPR) microscopy technique based on the combination of Lumera’s polymer and proprietary optic technologies offers parallel high-throughput analysis of biomolecular binding kinetics on high-density antibody microarrays ( > 1,500 [...]

A Demonstration of High-throughput Immunoassay and Small Molecule Binding on Protein Microarrays with SPR Microscopy

Kim G., Jiang L., Rathod P.K., Campbell C.T., Nishimoto A., Casasanta V., University of Washington, US

The use of Surface Plasmon Resonance (SPR) for the detection of biomolecular binding events at the nanometer scale is of great utility when expanded into microarray density formats. Protein microarray analysis is particularly well suited [...]

An Chip-based-Instant Protein Micro Array Formation and Detection System

Tseng F-G, Ho C.E., Chen M.H., Chen Y.F., Hung K.Y., Su C-J, Chen M.H., Chen Y.F., Huang H.M., Chieng C-C, National Tsing Hua University, TW

This paper proposes a novel protein micro arrayer employing 3-in-1 chip system, instantly delivering hundreds of biosamples in parallel for disease diagnosis. The 3-in-1chip system included: micro filling chip, micro stamper array and micro bio-reaction [...]

Immunosensing Using Fabricated protein Microarrays

Howell S.W., Inerowicz H.D., Guirl L., Regnier F., Reifenberger R., Purdue University, US

Patterned microarrays of antibodies to specific bacteria were used to perform a series of bacterial immunoassays of E. Coli 0157:H7 and Renibacterium Salmoninarum (RS). Microarrays were fabricated using microcontact printing (MCP) and characterized using scanning [...]

Direct Write Technology as a Tool to Rapidly Prototype Patterns of Biological and Electronic Systems

Ringeisen B.R., Chrisey D.B., Piqué A., Krizman D., Brooks M., Spargo B., Naval Research Laboratory, US

The full potential of modeling and simulations is only realized when it is based on experimental results under varied conditions and systems. A single tool to rapidly prototype electronic and biological circuits would enhance the [...]