photothermal therapy – TechConnect Briefs

Overcoming Challenges in Manufacturing Scale-Up of Plasmonic Gold Nanorods: Bringing Photothermal Therapy to the Clinic.

Pagliaro L., Siva Therapeutics Inc, US

Siva Therapeutics is developing a simple, safe, and effective adjunct cancer treatment termed Targeted Hyperthermia™, which generates therapeutic heat emanating from within solid tumors using systemically injected precision gold nanorods and an infrared light engine [...]

Theoretical Comparison of Optical and Photothermal Properties of Near-Infrared Plasmonic Nanoparticles

Liu K., Xue X., Furlani E.P., University at Buffalo, US

In this presentation, we use 3D computational models to compare the optical and photothermal behavior of plasmonic nanostructures that are commonly used for near-infrared (NIR) applications. These include SiO2@Au core-shell, Au nanocage and Au nanorod [...]

Self-Assembly and Optical Behavior of Magnetic-Plasmonic Nanostructures

Liu K., Xue X., Sukhotskiy V., Furlani E.P., University at Buffalo, US

We introduce a bottom-up method for the fabrication of nanostructured photonic media and demonstrate proof-of-principle using a multiphysics modeling approach. The method involves magnetic field-directed self-assembly of magnetic-plasmonic core-shell particles (e.g. Fe3O4@Au) into extended particle [...]

Plasmonic Nanocages as Photothermal Transducers for Nanobubble Cancer Therapy

Karampelas I.H., Liu K., Furlani E.P., University at Buffalo (SUNY), US

The ability to generate and control thermal energy with nanoscale resolution is finding increasing use in a variety of applications spanning the fields of nanoparticle synthesis, nanofabrication, bio-imaging and medical therapy [1, 2]. One of [...]

Gold Nanoshells With Micellar Core for The Delivery of Hydrophobic Chemotherapeutic and Cancer Photothermal Therapy

Lee S-Y, Shieh M.J., National Taiwan University, TW

Gold nanoshells have attracted great research interest because of its potential application in cancer photothermal therapy. In the present study, we established a multifunctional gold nanoshell that directly utilizing positively charged PDMA-b-PCL micelles as a [...]

Plasmonic Nanocages as Photothermal Transducers for Laser Induced Heating and Bubble Generation

Karampelas I.H., Alali F., Furlani E.P., SUNY-Buffalo, US

A series of new computational models is introduced to demonstrate several photonic and thermo-fluidic details of the photothermal process associated with nanosecond-pulsed, laser-heated gold nanocages. Such models can be used to simulate energy conversion within [...]

Plasmonic Nanocages as Photothermal Transducers for Laser Induced Heating and Bubble Generation

Karampelas I.H., Alali F., Furlani E.P., SUNY-Buffalo, US

A series of new computational models is introduced to demonstrate several photonic and thermo-fluidic details of the photothermal process associated with nanosecond-pulsed, laser-heated gold nanocages. Such models can be used to simulate energy conversion within [...]

A Multifunctional Theranostic Nanoplatform for Image-Guided Surgery and Intraoperative Therapy

Taratula O., Schumann C., Duong T., Taylor K.L., Taratula O., Oregon State University, US

Currently, only optimal surgical resection of all disease sites can improve survival of ovarian cancer patients. Even with the best microsurgical techniques, however, palpation and visual inspection for malignant tissue identification can result in microscopic [...]

Photothermal Characteristics study of PEGylated Gold Nanorods

Shih T-Y, Lin J-T., Tien C.C., Tseng P-L, Chen Y-H, Industrial Technology Research Institute, TW

Gold nanorods have a growing role in a diversity of medical applications especially in the area of hyperthermal therapy of tumor. Since localized temperature rising by laser irritation gold nanorods at near-IR frequency can induce [...]