nanoparticles – Page 20 – TechConnect Briefs

Plasmon nanoparticle-generated photothermal bubbles as universal biomedical agents

Hleb E.Y., Yakush N.A., Hafner J.H., Drezek R.A., McNew J.A., Lapotko D.O., A. V. Lykov Heat & Mass Transfer Institute, BY

We report the concept and preliminary experimental evaluation of the new optical methods and agent, whose properties provide tunable effect from non-invasive optical sensing to selective mechanical damage at nano-scale and in living tissues and [...]

Inhibitory Effects of Gold and Silver Nanoparticles on RSV Studied by Atomic Force

Boyoglu S., Vig K., Pfendt A., Pillai S., Willing G.A., Singh S.R., Alabama State University, US

Human Respiratory Syncytial Virus (RSV) causes severe lower respiratory tract infections in infants which may progress to pneumonia. RSV accounts for approximately 4,500 deaths and 90,000 hospitalizations in infants and children in the United States [...]

Process Development and Industrial Manufacturing of Nanotechnology-Based Pharmaceuticals

Hassan E., Gumudavelli S., Pharmaceutics International Inc. (Pii), US

Process design and development of oral, topical and parentral nanotechnology-based pharmaceuticals are presented. Factors affecting process output and scale-up choices for various dosage forms are discussed with emphasis on critical parameter control and optimization. For [...]

Paclitaxel-functionalized aspragalan-calcium phosphate nanoparticles

He Q., Zhang X.Z., Yaun W.M., Zhau D.M., Fang Z.Q., Gang X.H., Nanjing Medical University, CN

Paclitaxel (PTX) is an important anticancer agent. Its aqueous solubility is very low; hence the available formulation of PTX for clinical use consists of Cremophor EL, which has been associated with several hypersensitivity reactions. In [...]

Formulation and Development of Novel Insitu Nasal Gel Containing Glibenclamide Nanoparticles

Gohel M.C., Par R.K., Patel K.D., L.M. College Of Pharmacy, IN

To provide an alternative route (non-swallowing) and compliance to patient (controlled release), nasal delivery of sulfonylureas is one of the best option among other routes for type II diabetes. Glibenclamide was selected as a model [...]

Method of LANTCET for cancer diagnostics and treatment at cell level

Hleb E.Y., Zastinskaya I.A., Ilyukova I.I., Semenenya I.N., Hafner J.H., Hanna E.Y., Myers J.N., Zhdanok S.A., Lapotko D.O., A. V. Lykov Heat & Mass Transfer Institute, BY

We have developed the method of LANTCET (laser-activated nano-thermolysis as a cell elimination technology) for selective detection and destruction of individual tumor cells by generating intracellular photothermal bubbles around the clusters of gold nanoparticles. Bare [...]

Atomic Force Microscopy as a Tool for Research in Oncocytology

Reshetov I.V., Chissov V.I., Volchenco N.N., Sukharev S.S., Slavnova E.N., Ivanov Yu.S., P.A.Hertzen Moscow Research Oncological Institute (MROI), RU

Most of investigations have studied specimens prepared by complex techniques which are unusual for hospitals. In present paper Scanning Probe Microscopy (SPM) has been used for searching signs of malignancy in specimens prepared identically to [...]

Plasmonic Enhancement in InGaN/GaN MQW System with Au Nanoparticles

Llopis A., Lin J., Neogi A., Pereira S.M.S., University of North Texas, US

In this article we report experimental evidence of plasmon based enhancement of an InGaN/GaN MQW system using Au nanocrystals. Enhancement of the main peak along with a blue-shift and change in the angle dependent PL [...]

Analytical Transmission Electron Microscopy characterization of nano-structured materials

Sharma U., Susnitzky D., Evans Analytical Group, US

This article reviews applications of analytical transmission electron microscopy (TEM) to characterize nano-structured materials and devices. Several practical examples are provided that show the diverse imaging and microanalysis mechanisms available in a modern TEM. By [...]

Dispersed stabilized Pt nanoparticles synthesized from an organometallic precursor

Ramírez-Meneses E., Torres-Huerta A., Domínguez-Crespo M.A., Montiel-Palma V., Hernández-Tapia G., Cicata - IPN Unidad Altamira, MX

In electrocatalysis, carbon materials have been generally employed to support metallic nanoparticles for electrochemical applications. Many methods to prepare CNTs supported metal nanoparticles including electrochemical, microwave irradiation and wet chemical methods have been reported in [...]