nanoarray – TechConnect Briefs

SPRi signal amplification by organothiols-nanopattern

Lisboa P., Valsesia A., Mannelli I., Colpo P., Rossi F., JRC-European Commission, IT

A 2D crystalline nanoarray of organothiols has been used for enhancing the detection sensitivity of Surface Plasmon Resonance-based biosensor. In particular, an IgG/AbIgG immunoreaction has been monitored by Surface Plasmon Resonance imaging on nano-patterned surfaces [...]

From Particle Self-Assembly to the Creation of Biologically Relevant Nanopatterns

Blättler T.M., Binkert A., Reimhult E., Textor M., Vörös J., ETH Zürich, CH

Nanopatterns are becoming increasingly popular in the field of bioscience and bioengineering because they provide novel tools to address biological problems. For example, protein nanoarrays not only enable molecular level statistics of binding events but [...]

New Light Induced Molecular Switch allows Sterically Oriented Micrometer Sized Immobilization of Biomolecules

Snabe T., Neves-Petersen M.T., Fojan P., Klitgaard S., Neves-Petersen M.T., Petersen S.B., Aalborg University, DK

Fundamental knowledge on protein structures and the effect of ultraviolet light on these structures has paved the way for the development of a unique light-based immobilization technology that allows oriented protein immobilization onto micrometer sized [...]

Development of Nano-sized Protein Arrays using Block Copolymer Self-Assemblies

Jung H-T, Jung J-M, Kwon K.Y., Ha T-H, Chung B.H., Jung H-T, Jung J-M, Korea Advanced Institute of Science and Technology, KR

The single molecule approach is potentially of great technological interest as a complementary means to obtain information about protein conformation or molecular interaction. The measurement for molecular interaction in single molecule level requires that the [...]

Functional Nanoarrays for Protein Biomarker Profiling

Lynch M., Mosher C., Huff J., Nettikadan S., Xu J., Henderson E., BioForce Nanosciences, Inc., US

The success of microarrays for analyzing nucleic acid and, more recently, protein-protein interactions illustrates the advantages of bioassay miniaturization. However, the current level of miniaturization of useful bioanalytical tools still creates limits in terms of [...]