molecular imaging – TechConnect Briefs

Gold Nanoparticle Bioconjugates for Biomolecular Imaging and Detection

Liu X., Dai Q., Coutts J., Austin L., Knowles G., Huo Q., University of Central Florida, US

Gold nanoparticles and colloids have been used for a long time in biomolecular imaging and detection. With further understanding on many of the electrical and optical properties of gold nanoparticles revealed recently, the application of [...]

Gold Nano-Probes as Targeted CT Contrast Agents for In-vivo cancer Imaging

Popovtzer A., Popovtzer R., Agrawal A., Shlomi M., Popovtzer A., Popovtzer R., Balter J., Carey T.E., Kopelman R., University of Michigan, US

This research describes a new class of immuno-targeted and cancer specific CT contrast agents, which enable CT imaging of cancer at cellular and molecular resolution. The method is based on the development of gold nano-probes [...]

Scalable Fabrication of Polymeric and Organic Nanomaterials using Particle Replication in Non-wetting Templates (PRINT) and Imprint Lithography

Maynor B.W., Denison G.M., Rolland J.P., DeSimone J.M., Liquidia Technologies, US

We have developed scalable, “top-down” nanofabrication methodologies for the fabrication of polymeric and organic nanostructures for nanobiotechnology and materials engineering. These techniques use novel perfluoropolyether (PFPE) elastomers that possess superior nanoimprinting properties, including error-free nanoscale [...]

New Applications of Nanoparticles in Cardiovascular Imaging

Sharma R.R., FAMU-FSU College of Engineering, US

Nanotechnology involves working at the atomic, molecular, and macromolecular levels including imaging. Recently, four areas have emerged in cardiovascular imaging:1.Targeted therapeutics: delivering drugs where they are needed; 2.Tissue engineering to replace defective valves, damaged heart [...]

Molecular Targeted Functional, Cellular and Molecular Imaging of Atherosclerosis with Antibody-conjugated Superparamagnetic Particles Using Magnetic Resonance

Sharma R., Katz J.K., Haik Y., Chen C-J., FAMU-FSU College of Engineering, US

Background: Magnetic Resonance Imaging (MRI) is a powerful non-invasive technique that provides high-resolution anatomical images of biological tssue based on their inherent physio-chemical properties. The signal from MRI can be modulated by contrast agents, which [...]