iron oxide nanoparticles – TechConnect Briefs

Nano-Organocatalysts: new magnetically retrievable tools for enantioselective synthesis

Nehlig E., Motte L., Guénin E., Université Paris, FR

We report the elaboration of new organocatalyst functionalized superparamagnetic iron oxide nanoparticles that can act as a new enantioselective organocatalyst. Differents organocatalysts are grafted using two different methodologies on a nanoplateform constituted of 10 nm [...]

Nano-Organocatalysts: new magnetically retrievable tools for enantioselective synthesis

Nehlig E., Motte L., Guénin E., Université Paris, FR

We report the elaboration of new organocatalyst functionalized superparamagnetic iron oxide nanoparticles that can act as a new enantioselective organocatalyst. Differents organocatalysts are grafted using two different methodologies on a nanoplateform constituted of 10 nm [...]

Clusters of Iron Oxide Nanoparticles for Efficient Magnetic Resonance Imaging

Lai P.S., Lai S.M., Lai P.S., Lai S.M., National Chung Hsing University, TW

Recently, self-assembling clusters of metal nanoparticles have been extensively investigated in various fields. To prepare these clusters, various ionic surfactants, have been employed as stabilizers or emulsifiers to form water-dispersed spherical clusters. However, these ionic [...]

Synthesis, Characterization and Toxic Metal-Binding Ability of Poly(γ-glutamic acid)-coated Superparamagnetic Nanoparticles

Chen B.H., Inbaraj B.S., Fu Jen University, TW

Superparamagnetic iron oxide nanoparticles (SPIONPs) coated with a non-toxic, edible biopolymer poly(-glutamic acid) (PGA-coated SPIONs) were synthesized by co-precipitation method, characterized and evaluated for their possible toxic metal-binding ability in the treatment of metal intoxication [...]

Synthesis, Characterization and Antibacterial Activity of Glycol Chitosan Modified Superparamagnetic Nanoparticles

Chen B.H., Inbaraj B.S., Fu Jen University, TW

Superparamagnetic iron oxide nanoparticles (IONPs) are particularly attractive as antibacterial agents owing to their precise bacterial biofilm and cell targeting in vivo achieved by magnetic driving. In this work, superparamagnetic IONPs modified with water-soluble glycol [...]

From Rational Design to Probe Optimization: the Role of Nanoparticle Valency in Single Cancer Cell Detection in Blood via Magnetic Relaxation

Kaittanis C., Santra S., Perez J.M., University of Central Florida, US

The conjugation of targeting ligands to iron oxide nanoparticles has achieved the development of specific assays for the detection of biomedical targets through magnetic relaxation. However, limited studies investigated how the nanoparticle valency modulates the [...]

Identification of Molecular-Mimicry-Based Ligands for Cholera Diagnostics using Magnetic Relaxation

Santiesteban O.J., Kaittanis C., Banerjee T., Santra S., Teter K., Perez J.M., University of Central Florida, US

Magnetic nanosensors (MRnS) offer multiple benefits that can be used to design sensitive and robust diagnostic tools. High sensitivity, stability, and ease of surface modification make this approach a strong contender against the more commonly [...]

New Multimodal Iron Oxide Nanoparticles as Nanotools for Cancer

Benyettou F., Chebbi I., Lalatonne Y., Sainte-Catherine O., Di Benedetto M., Lecouvey M., Seksek O., Motte L., Université Paris 13, FR

The goal of this project is to elaborate new multifunctional magnetic nanovectors to vectorize biological interest molecules for therapy and diagnostic applications. Indeed, iron oxide nanoparticles, tanks to their magnetic properties, are used as contrast [...]

Identification of bacterial drug resistance in blood

Kaittanis C., Nath S., Perez J.M., University of Central Florida, US

Development of antibiotic resistance by microorganisms has been on the rise in recent years. Therefore, identifying drug resistant strains and effective antibiotic agents is critical. Traditional microbiological methods assess antimicrobial susceptibility within 24 to 48 [...]

Strategies for enhanced brain tumor accumulation of magnetic nanoparticles for potential drug delivery

Chertok B., David A.E., Yang V.C., University of Michigan, US

The purpose of this study was to elucidate strategies to enhance magnetically mediated accumulation of iron-oxide-based nanoparticles in brain tumors for potential localized delivery of chemotherapeutic agents. In particular, we evaluated administration of the nanoparticles [...]