immune response – TechConnect Briefs

Dex40-GTMAC3, modified dextran as a novel heparin antagonist

Kalaska B., Kaminski K., Sokolowska E., Czaplicki D., Kujdowicz M., Stalinska K., Szczubialka K., Bereta J., Pawlak D., Nowakowska M., Mogielnicki A., Medical University of Bialystok, PL

Protamine is the only registered antidote preventing bleeding of patients treated with unfractionated heparin (UFH). However protamine may induce anaphylactic shock or serious hypotension. We aimed to develop an alternative fully synthetic UFH antidote as [...]

Efficiency of different chitosan and its derivative nanoparticles for delivery of recombinant plasmid of Tibetan pig interleukin-7 gene and regulation effect in vivo on immune responses of mice

Wan X.P., Wang Z.Z., Yang X., Lang G., Sun W.K., Chen Y-H, Li J.L., Liu R., Gu Y.R., Liu R., Wang Z.Z., Lu X.B., Gao R., Sichuan University, CN

For sake of developing safe and effective technique to deliver and express animal immune gene in vivo to enhance comprehensive immunity of animal against infectious disease, the interleukin-7 gene of Tibetan pig was firstly cloned [...]