imaging – TechConnect Briefs

Gamma-Ray Raster Imaging with Robotic Data Collection

Aucott T., Wells W., Siddiqi M., Savannah River National Laboratory, US

Currently, in order to create gamma-ray images, some form of collimation is required. The foremost imaging techniques either require physical collimation (such as the heavy shielding required for a pinhole imager) or restrictive algorithms (such [...]

Personalized nanomedicine for the treatment of vascular hypertension in polycystic kidney disease models

Pala R., Nauli S.M., University of California Irvine, US

In our current study, we designed a nanomedical device for the treatment of vascular hypertension in polycystic kidney disease (PKD) model through cilia targeting. We generated and compared two different metal and polymer cilia-targeted nanoparticle [...]

Photoswitching Nanoparticles Enable Innovative Bioimaging Technologies

Wan W., Li A., Washington State Universoty, US

Nanoparticles have evolved to be the carriers of multiple technologies, which garnished unprecedented power in molecular imaging. For example in bioimaging, a single fluorescent probe is usually lost in the ocean of myriad other molecules [...]

Advanced Packaging for Next Generation Imaging and Sensor Devices

Kulick J., Indiana Integrated Circuits, LLC, US

Quilt Packaging is a unique and versatile edge-interconnect technology that utilizes “nodule” structures that extend out from the vertical facets along the edges of chips to allow for inter-chip communication. QP has demonstrated world-record chip-to-chip [...]

Multilayer optical strip for illumination, imaging and analysis

Gomez-Gonzalez E., Marquez-Rivas J., Perales-Esteve M.A., Mayorga-Buiza M.J., University of Seville, ES

An optical device (multilayer optical strip, MOS) is presented. It is composed of a small-sized, strip-shaped, multilayer, planar structure connected to a control unit. Active and passive optical elements allow for controlling the properties, spatial [...]

Imaging and Spectroscopy of the Au Nanoclusters in the YSZ Films by Ballistic Electron/Hole Emission Microscopy

Filatov D.O., Guseinov D.V., Antonov I.A., Gorshkov O.N., Bobrov A.I., Pavlov D.A., N.I.Lobachevskii University of Nizhny Novgorod, RU

We report on the first time application of Ballistic Electron/Hole Emission Microscopy (BEEM/BHEM) to imaging and spectroscopy of metal NCs in the ultrathin dielectric films. We studied the yttria stabilized zirconia (YSZ) films (12% mol. [...]

Encapsulation of nanoparticles with multifunctional, cross-linkable diblock copolymers for biomedicine

Schmidtke C., Ostermann J., Tran H., Pöselt E., Kloust H., Niehaus J., Becker S., Kreuziger A., Werner K., Pietsch A., Weller H., University of Hamburg, DE

We would like to present a micellular encapsulation method for nanoparticles (quantum dots, iron oxides, gold) which is based on a ligand exchange procedure of native ligands with a prepolymer poly(isoprene)-diethylentriamine (PI-N3) and subsequent ligand [...]

Raman Spectroscopy hyperspectral imager based on Bragg Tunable Filters

Marcet S., Verhaegen M., Blais-Ouellette S., Martel R., Photon etc., CA

A new type of Raman spectroscopy hyperspectral imager based on Bragg tunable filter has been developed by University of Montreal and Photon etc. The technology of Bragg tunable filter significantly reduces the acquisition time by [...]

Polymersomes and Imaging: A Quantitative Approach

Joseph A.S., Brown N.J., Battaglia G., University of Sheffield, UK

Nano-sized carriers are widely used as imaging tools. Quantification of the amount of carrier delivered provides useful informations in development and testing stages. This work describes a HPLC method to quantify fluorescent labelled polymersomes. Polymersomes [...]

Label-free Raman Micro-Spectral Imaging of the Microenvironment of PANC-1 Spheroids

Chernenko T., Shah R., Zuser E., Diem M., Amiji M., Northeastern University, US

Spheroids are 3D tumor models, which reflect diverse properties of the growing tumor. Due to its avascular microenvironment, initial tumor growth patterns as well as subsequent tumor-core biochemistry may be studied in depth, from which [...]