HIV – TechConnect Briefs

Nanostructured Lipid Carriers to Deliver HIV p24 Antigen and CpG Immunostimulant in Mice and Non-Human Primates Immunogenicity Studies

Bayon E., Morlieras J., Gosse L., Gonon A., Bosquet N., Le Grand R., Marche P.N., Navarro F.P., CEA-LETI, FR

Fighting HIV pandemic is one of today’s major health priorities and vaccination remains the most challenging issue against HIV propagation. Until now, the best vaccine candidate showed only 30% protection in RV144 clinical trial [1]. [...]

Relaxation Time Constants of Nanometals in Human Tissues and Clinical Applications

Sharma A., Sharma R., Sharma A., Sharma R., Center of Nanotechnology, IN

The metals are in abundance in human body in biofluids, blood, cerebrospinal fluid, saliva, lymph. These metals are found in free and bound forms in each tissue and their amount is tissue specific. The mechanism [...]

Extended Applications of Picomolar Technology to Measure Immunoactive Biomarkers

Shriniwas B.D., Sharma A., Sharma R., Sharma A., Sharma R., RTM Nagpur University, IN

The picotechnology extended use in marine and biology applications are reported after our report on picotechnology to measure picomolar quantities of single stranded DNA in evaluation of Texotere chemosensitivity (TCRT,2008,28(6):175). Lead and mercury poisoning is [...]

Cell-mediated, heat-based therapy for combating HIV infection

Denver H.T., de Noronha C.M., Borca-Tasciuc D-A., Rensselaer Polytechnic Institute, US

There is an increased interest in developing alternative therapies to combat deadly infectious disease including HIV. This work investigates the fundamentals of a novel, nanoparticle-based potential treatment method employing macrophage cells. Macrophages are a very [...]

Nano-Biotechnology toward Diagnostic Industry: Obstacles and Opportunities

Esfandyarpour H., Stanford, US

Biosensing of infectious agents should be ideally real-time, multiplexed, sensitive and specific. While no single device thus far have demonstrated superiority with respect to all these qualities, many of the upcoming nanomaterial-based sensors described in [...]