delivery system – TechConnect Briefs

Nanosystem for targeting Treg in vivo

Bottini M., Bottini N., Sacchetti C., Rapini N., Rosato N., Magrini A., Bottini M., Bottini N., Sanford Burnham Medical Research Institute, US

Due to their ability to suppress the activity of autoreactive cells, “natural” CD4+ CD25high FoxP3+ T cells (Treg) are important drug targets for autoimmune diseases and malignancies. Immunological studies are revealing a growing subset of [...]

Preparation of BSA Nanoparticles by desolvation method as a delivery system for nutraceuticals

Sadeghi R., Kalbasi A., Moosavi-Movahedi A.A., Karimi M., Kokini J., University of Illinois at Urbana-Champaign, US

The production of biocompatible nanoparticles (NPs) is one the most attractive research areas in food and drug sciences. The more the ratio of desolvating agents the bigger the particles size. The best ratio for ethanol, [...]

A “leukolike” multistage delivery system to overcome biological barriers

Qauttrocchi N., Chiappini C., Cooper L., Ferrari M., Tasciotti E., University of Texas Health Science Center, US

Delivery systems based on Nanoporous Silicon Particles (NSPs) have been proposed as ideal candidates for the targeted release of drug and contrast agents to tumor sites as porous silicon is biocompatible, biodegradable and easy to [...]