amyloid beta peptide – TechConnect Briefs

Exacerbation of amyloid beta peptide and Tau protein in the cerebrospinal fluid following Traumatic Brain Injury at Hot Environment. Neuroproetction by TiO2 nanowired delivery of cerebrolysin with tau antibodies

Sharma A., Sharma H.S., Lafuente J.V., Muresanua D.F., Castellani R.J., Smith M.A., Nozari A., Patnaik R., Tian Z.R., Ozkizilcik A., Mössler H., Sharma A., Sharma H.S., Uppsala University, Uppsala, SE

Military personnel are often exposed to high environmental temperature in desert areas during combat operations. Since traumatic brain injury (TBI) is quite common in combat operation, a possibility exists that hot environment (HE) could affect [...]

Nanodelivery of cerebrolysin reduces depressive stress induced exacerbation of Alzheimer’s disease brain pathology following amyloid-beta peptide infusion

Sharma A., Sharma H.S., Muresanu D.F., Lafuente J.V., Patnaik R., Tian Z.R., Ozkizilcik A., Castellani R.J., Mössler H., Sharma A., Sharma H.S., Uppsala University, SE

Military personnel are highly vulnerable to Alzheimer’s disease (AD). This is because of the fact that severe stress of trauma, sleep deprivation or combat stress causes increased deposition of amyloid beta peptide in the cerebrospinal [...]

Nanodelivery of Cerebrolsyin in combination with neprilysin induces neuroprotection in Alzheimer’s Disease pathology following brain injury

Sharma A., Sharma H.S., Muresanu D.F., Lafuente J.V., Patnaik R., Tian Z.R., Ozikzilcik A., Mössler H., Sharma A., Sharma H.S., Uppsala University, SE

Neprilysin (NPL) is an endogenous enzyme that functions as rate-limiting step in amyloid-beta peptide (AβP) degradation. There are reasons to believe that an imbalance between production and clearance of AβP results in its accumulation leading [...]