Stueckle T. – TechConnect Briefs

Role of Caveolin-1 in Carbon Nanotube-Induced Stem-Like Cells and Tumorigenesis

Luanpitpong S., Wang L., Castranova V., Stueckle T., Rojanasakul Y., West Virginia University, US

Carbon nanotubes (CNT) hold great promise to create new and better products, but their long-term adverse health effects are a major concern. The objective of this study was to develop an in vitro model for [...]

In vitro Model for Identifying Subchronic Carbon Nanotube Exposure and Lung Cancer Gene Markers

Stueckle T., Davidson D., Derk R., Meighan T., Castranova V., Rojanasakul Y., Wang L., National Institute for Occupational Safety and Health, US

Concern for increased risk of carbon nanotube-associated lung disease, including carcinogenesis, has been raised due to asbestos-like characteristics. To date, no particle specific nanomaterial exposure or lung cancer markers have been identified. Here, we use [...]

In Vitro Assessment of Nano-Cerium Oxide (nCeO2) and Nano-Ferric Oxide (nFe2O3) on Fibrogenic and Carcinogenic Potential

Wang L., Davidson D., Stueckle T., Derk R., Chen M., Sotiriou G.A., Demokritou P., Luanpitpong S., Ma J., Mercer R.R., Castranova V., Rojanasakul Y., National Institute for Occupational Safety and Health, US

Goal of the present study is to investigate the specific cellular responses to nCeO2 and nFe2O3 in various lung cell types and develop an in vitro chronic exposure model to predict the potential fibrogenic and [...]