Singh S.R. – Page 3 – TechConnect Briefs

Antibacterial effect of Silver Carbon Nanotubes against Multi-drug resistant Pseudomonas aeruginosa

Dosunmu E., Pillai S., Vig K., Singh S.R., Dennis V.A., Coats M., Alabama State University, US

Silver carbon nanotubes AgCNT inhibited the growth of P. aeruginosa at the lowest concentration of 60 µg/ml for at least 12 hr. Further studies of structural and morphological changes would further elucidate the mechanism of [...]

Smaller sizes of Ag-PVP Nanoparticles Control Inflammatory Responses, and Reduce CD80 and CD86 Expression Levels, in Macrophages Infected with Chlamydia trachomatis

Yilma A.N., Singh S.R., Dennis V.A., Alabama State University, US

Chlamydia trachomatis is an important cause of sexually transmitted infection that can manifest itself as either acute cervicitis, pelvic inflammatory disease, and more commonly as a chronic asymptomatic infection. Early intervention strategies that can reduce [...]

Supermagnatic Iron Oxide Nanoparticles Toxicity to Mammalian Cells

Vig K., Tiwari P., Parveen A., Rangari V., Singh S.R., Alabama State University, US

The present study investigates the development of superparamagnetic iron oxide nanoparticles as a controlled release drug formulation and use as anticancer therapeutic agents. Iron oxide nanoparticles (IONPs) were synthesized using ultrasonic irradiation of iron pentacarbonyl [...]

Encapsulation and Characterization of BSA in PLA-PEG Nanoparticles as a Model for Chlamydia trachomatis rMOMP-278 Protein Nanovaccine Delivery System

Taha M., Singh S.R., Moore C., Agee R., Dennis V.A., Alabama State University, US

Chlamydia trachomatis is a major human health pathogen because it is the most reported sexually transmitted disease. There is no effective mucosal vaccine against Chlamydia. One of the major problems of the C.trachomatis vaccine development [...]

Development of PHEMA-Chitosan nanospheres and encapsulation of RSV-F DNA vaccine

Eroglu E., Waffo A.B., Dennis V.A., Singh S.R., Alabama State University, US

Respiratory Syncytial Virus (RSV) causes serious lower respiratory tract diseases among infants. Unfortunately, no effective vaccine to prevent RSV infection has been developed. RSV fusion gene (RSV-F) is conserved among various strains of RSV. Therefore, [...]

The Intracellular Co- localizations of Different Size of Gold Nanoparticles

Boyoglu C., Boyoglu-Barnum S., Boyoglu-Barnum S., Soni S., He Q., Willing G., Miller M.E., Singh S.R., Alabama State University, US

Gold nanoparticles (GNPs) are widely used in biological and clinical applications due to their favorable optical and chemical properties. The scientific understanding of the intracellular uptake of GNP is required for biomedical applications, such as [...]

Evidence of the Anti-inflammatory effect of Silver- polyvinyl Pyrrolidone Nanoparticles (Ag-PVP) in Chlamydia trachomatis infected Macrophages and HeLa Cells

Yilma A.N., Singh S.R., Murtada T.A., Fairley S., Subbarayan P., Dennis V.A., Alabama State University, US

Chlamydia trachomatis is the leading cause of bacterial sexually transmitted diseases (STDs) in the USA, and therefore, of major public health significance. C. trachomatis invades the mucosal surface of the female genital tract consequently triggering [...]

Authors: Singh S.R.