Ostermann J. – TechConnect Briefs

Uptake Behavior of Glycoconjugated and Micellar-Encapsulated Quantum Dots on HeLa Cervical Cancer Cells

Merkl J.-P., Schmidtke C., Safi M., Muroski M., Alpers D., Tran H., Ostermann J., Kreuziger A.-M., Strouse G., Mattoussi H., Weller H., University of Hamburg, DE

Glyconanomaterials are of great interest for bio-imaging to understand biological processes, for instance metabolism, cell-cell or virus-cell interactions, gluconeogenesis, and cancer. Herein, we present a strategy for the biofunctionalization of fluorescent quantum dots (QDs) from [...]

Encapsulation of nanoparticles with multifunctional, cross-linkable diblock copolymers for biomedicine

Schmidtke C., Ostermann J., Tran H., Pöselt E., Kloust H., Niehaus J., Becker S., Kreuziger A., Werner K., Pietsch A., Weller H., University of Hamburg, DE

We would like to present a micellular encapsulation method for nanoparticles (quantum dots, iron oxides, gold) which is based on a ligand exchange procedure of native ligands with a prepolymer poly(isoprene)-diethylentriamine (PI-N3) and subsequent ligand [...]