Leung S.W. – TechConnect Briefs

Comprehensive Analysis of High Performing Electrochemical Biosensors and Their Applications: II, System Update

Leung S.W., Lai J.C.K., Idaho State University, US

We have mounted 5 different biocatalysts on a sensor platform to examine the performance of this electrochemical sensing system for the detection of different biomolecules/metabolites and environmental important molecules, with such we also compared how [...]

MCM-41 and Functionalized MCM-41 as Adsorbents to Remove Heavy Metals and Hardness from Contaminated Water and Groundwater

Leung S.W., Basnet N., Dejesus K., Lai J.C.K., Idaho State University, US

Mining operating and abandoned mines often have resulted in waste rock dumps and open pits that contain materials high in heavy metals and toxic elements. These contaminants are known to be present in groundwater, surface [...]

Cyanide Detection by Highly Modified Sol-Gel Biocomposite Sensor

Mozneb S., Lai J.C.K., Leung S.W., Idaho State University, US

Cyanide is an important industrial chemical but is also very toxic. Cyanide binds strongly with hemoglobin than that of oxygen which causes histoxic hypoxia, if cyanide is ingested into the bloodstream. This pairing reaction can [...]

Comprehensive Analysis of High Performing Electrochemical Biosensors and Their Applications

Assan D., Lai J.C.K., Leung S.W., Idaho State University, US

We have mounted 5 different biocatalysts on a sensor platform to examine the performance of this electrochemical sensing system for the detection of different biomolecules/metabolites and environmental important molecules, with such we also compared how [...]

Co-Culturing Dorsal Root Ganglion Neurons with Schwann Cells Protects Them Against the Cytotoxic Effects of Silver Nanoparticles

Gao W., Leung S.W., Bhushan A., Lai J.C.K., Idaho State University College of Pharmacy, US

Because of their presumed inertness, silver nanoparticles are increasing employed in many consumer products. Nonetheless, their environmental and health hazard impact are not understood. Our previous studies led us to develop a co-culture model consisting [...]

Schwann Cells and Dorsal Root Ganglion Neurons Are Differentially Susceptible to Oxidative Stress Induced by Silicon Dioxide Nanoparticles

Lai J.C.K., Jaiswal A.R., Idikuda V.K., Pfau J., Bhushan A., Leung S.W., Idaho State University College of Pharmacy, US

Silicon dioxide (SiO2) particles, including nanoparticles, have been increasing employed in diverse industrial and biomedical applications including those in drug formulations, food, and cosmetics as SiO2 has been generally regarded as a non-toxic substance. However, [...]

A New Biocomposite Electrode Sensor for the Detection of Oxidative Reactions

Assan D., Gao X., Lai J.C.K., Leung S.W., Idaho State University, US

Hemoglobin has a very strong affinity with oxygen and thus is a good catalyst to carry oxygen for many oxidation reactions. Many researchers have explored this property of hemoglobin to develop sensors for the detection [...]

Zinc Oxide Nanoparticles Induced Apoptosis and Necrosis in Human Neuroblastoma and Astrocytoma Cells

Lai J.C.K., Lai M.B., Balaraju A.K., Neti A., Lai J.C.K., Lai M.B., Tadinada S.M., Idikuda V.K., Singh M.R.M., Mukka K., Pfau J., Bhushan A., Leung S.W., Idaho State University College of Pharmacy, US

Because of their escalating uses in industrial and biomedical applications, humans are increasing exposed to nanoparticles in occupational and other environmental settings. However, the environmental safety and health impact of such particles have not been [...]

Cytotoxic Effects of Silver and Gold Nanoparticles in Human Glioblastoma U87 Cells

Gao W., Leung S.W., Bhushan A., Lai J.C.K., Idaho State University College of Pharmacy, US

Nanoparticles have contributed significantly to the design of new drug delivery and targeting in cancer chemotherapy. Consequently, some of the desirable qualities of silver and gold nanoparticles have prompted their novel applications in cancer nanobiotechnology. [...]

Detection of Prostate-Specific Antigen (PSA) with an Ultra High Performance Electrode Modified with Sol-Gel Au Nanoparticles

Leung S.W., Mozneb S., Lai J.C.K., Assan D., Idaho State University, US

Prostate cancer is one of the leading cancer causing death in men, especially in western developed countries. Prostate-specific antigen (PSA) is one of the biomarker that can be used to diagnose prostate cancer, although using [...]