Lagae L. – TechConnect Briefs

A double-bead sandwich assay for protein detection in serum based on localized surface plasmon resonance

Jans H., Jans K., Jans H., Jans K., Stakenborg T., Borghs G., Maes G., Lagae L., IMEC, BE

In this study, the importance of pre-concentration is clearly demonstrated for the covalent immobilization of various proteins to magnetic nanoparticles through mild carbodiimide activation. Additionally, the covalently biofunctionalized magnetic nanoparticles are employed in a double-bead [...]

Enhanced Mass Sensing for Nanomechanical Resonators

De Greve K., De Vlaminck I., De Greve K., De Vlaminck I., Naulaerts R., Sivasubramaniam V., Lagae L., Tilmans H.A.C., Borghs G., IMEC, BE

A new method for improving the mass detection limit of nanomechanical resonators in crystalline silicon, compatible with scaling, is demonstrated. Clamped-clamped silicon beam resonators are fabricated with a non-rectangular, ‘diabolo’ cross-section starting from SOI wafers. [...]