Kissinger P.T. – TechConnect Briefs

Nanobiomimetic Structured Organo-Metal Devices Direct Rapid Real-time Monitor Atto Molarities of ATP in Biological Specimens

Chen E.T., Thornton J.T., Duh S-H, Kissinger P.T., Advanced Biomimetic Sensors, Inc., US

Real-time monitoring of ATP in biological specimens is a convenient means to monitor the hygiene in healthcare units and for medical devices. Rapid and precise monitoring of ATP has been in strong demand. We report [...]

Utilization of the Flexible Josephson Toroidal Junctions for Self- Powering 150K Super lattice Bits Having Non-volatile Memory Storage in One Device Assembly at Room Temperature

Chen E.T., Thornton J.T., Duh S-H, Kissinger P.T., Advanced Biomimetic Sensors, Inc., US

We report a self-powered multiple flexible Josephson junction-based toroidal (FJJT) array superconductive/mem-element super lattice bit (Sulbit) device for quantum computing with non-volatile memory and non-dissipation energy storage in room temperature in one device assembly developed. [...]

Discovering of Collagen-1’s Role in Producing Superconducting Current in Nanobiomimetic Superlattice Structured Organometallic Devices at Room Temperature Enabled Direct Quantitation of Sub pg/mL Collagen-1 by a Voltage and a Cyclic Voltammetry Method

Chen E.T., Thornton J.T., Kissinger P.T., Duh S-H, Advanced Biomimetic Sensors, Inc., US

Cooper pair electrons producing superconducting current in near zero Kelvin temperature at the Josephson-junction in the superconductors show its potential utilities. Could also a superconducting current produced by a superlattice organometallic device enable direct detection [...]

Nanobiomimetic Superlattice Superconductive/Memristive Organometallic Devices at Room Temperature Serve as Chronoamperometric Sensors for sub fg/mL Collagen-1 Detection in Human Serum

Chen E.T., Thornton J.T., Kissinger P.T., Duh S-H, Advanced Biomimetic Sensors, Inc., US

Superconductive/Memristive devices have potential applications in supercomputing and in health industry was proposed in literature. Clinically detection range at low concentration for collagen-1 is difficult to accomplish due to the denaturing of protein Matrix Matelloprotinase-2 [...]

Organic Nanobiomimetic Memristor/Memcapacitor Devices Ultrasensitive Direct Detect Matrix Matelloproteinase-2 in Human Serum

Chen E.T., Thornton J., Duh S-H, Advanced Biomimetic Sensors, US

Matrix Matelloproteinase-2 (MMP-2) plays a key role in many diseases. A new type of dual-functioning device was developed for fast, direct ultrasensitive detection of MMP-2 using NIST SRM965A reference human serum specimens under label-free, probe-free [...]

Nanobiomimetic Memristor/memcapacitors’ Function as a Voltage Sensor for Direct and Reagent-free Detection of sub pg Lipopolysaccharide (LPS) in Milks for Children

Duh S-H, Thornton J., Kissinger P.T., Chen E.T., advanced biomimetic sensnors, inc, US

Lipopolysaccharide (LPS) is a common endotoxin from E. Coli bacteria, and is the major source causing infection diseases over 20 million people worldwide. Lack of sensitivity and high imprecision from common commercial test methods are [...]

Nanobiomimetic Memristor/Memcapacitor Devices Used for Direct and Reagent-less Detection of Sub pM Acetyl Coenzyme A in Milks

Duh S-H, Thornton J., Kissinger P.T., Chen E.T., advanced biomimetic sensnors, inc, US

Acetyl co-enzyme A (AcCoA) is a leading substrate in a large variety of enzyme-catalyzed reactions, such as for choline acetyltransferase and acetylcholinesterase. They are critical to energy production, metabolism, memory, cell proliferation and early childhood [...]

Acetylcholine Repairs the Amyloid-beta Damage on Brain Circuitry and Memory Loss From a “Mutated Biomimetic Acetylcholinesterase” Neuronal Memcapacitor During Slow-Wave Sleeping

Thornton J., Mulchi Jr. C., Kissinger P.T., Chen E.T., Advanced Biomimetic Sensors, Inc., US

Amyloid-beta (A) plaque accumulation in the brain has been recognized to be associated with Alzheimer’s. Using artificial neuronal devices under controlled conditions, step-by-steps mimicking the A damages to neuronal circuitry is desirable, because of convenience [...]

A Nanobiomimetic Neuronal Memcapacitor Serves as a Voltage Sensor and an Amperometry Sensor for Reagent-less Direct Detection of Sub pM Soluble Amyloid-beta

Duh S-H, Thornton J., Kissinger P.T., Chen E.T., Advanced Biomimetic Sensors, Inc., US

Amyloid-beta (A) plaque accumulation in the brain has been recognized to be associated with Alzheimer’s and dementia. Challenges of quantitation of Ab are the instability of soluble Ab1-42 and the protein interference plus the time [...]

Nanostructured Biomimetic Memristor Sensors Used for Therapeutic Monitoring of the Brain Cancer

Chen E.T., Thornton J., Ngatchou C., Duh S-H, Kissinger P.T., Advanced Biomimetic Sensors, Inc., US

Current technology is not available to provide a portable, simple and accurate real-time monitoring and treatment of cancers simultaneously in an early stage at a clinical setting. Challenges for developing such a tool, include the [...]