Accurate High-throughput Gene Synthesis Using Programmable DNA Microfluidic Microchips
Church G.M., Gao X., Gong H., Gulari E., Sheng N., Tian J., Zhou X., Harvard Medical School/Genetics, US
Testing the deluge of hypotheses flowing from genomics and systems biology demands accurate and cost-effective gene and genome synthesis. Here we describe a microchip-based technology for multiplex gene synthesis. Pools of thousands of "construction" oligonucleotides [...]