Cho K. – TechConnect Briefs

Hybrid biosensor for the early diagnosis of breast cancer

Cho K., Chong S., Chong S., Park E., Lee J-H., Luminescent MD, LLC, US

A cost-effective and novel hybrid biosensor using the combination of antibody and DNA aptamer was developed for the early diagnosis of breast cancer. 1,1’-oxalyldiimidazle chemiluminescence (ODI-CL) was applied as a detector of the hybrid biosensor. [...]

Breast cancer diagnosis system using the combination of carcinoembryonic antigen aptamer, horseradish peroxidase-mimic hemin, and graphene sheet

Chong S., Cho K., Chong S., Khang H.J., Lee J-H., Lee S-Y, Kim Y.T., Lee J-H., Lee S-Y, Luminescent MD, LLC, US

In order to early diagnose breast cancer with the rapid quantification of carcinoembryonic antigen (CEA) in human serum, highly sensitive DNA aptasensor with 1,1-oxalyldiimidazole chemiluminescence (ODI-CL) detection was developed using the combination of CEA aptamer, [...]

Microkinetic Study of Oxygenate and Hydrocarbon Formation from Syngas on Rhodium and Cobalt Surfaces: Effect of Site Structure on Catalytic Cycles

Kapur N., Sampara C., Hao X., Hyun J., Shan B., Nicholas J.B., Davis B., Cho K., Nanostellar Inc., US

Syngas reformation into fuels is an attractive opportunity to diversify away from petroleum and address energy-dependency concerns. Rh and Co-based catalysts used within Fischer-Tropsch (FT) process selectively convert syngas into oxygenates and hydrocarbons respectively but [...]

Microkinetic Study of Oxygenate and Hydrocarbon Formation from Syngas on Rhodium and Cobalt Surfaces: Effect of Site Structure on Catalytic Cycles

Kapur N., Sampara C., Hao X., Hyun J., Shan B., Nicholas J.B., Davis B., Cho K., Nanostellar Inc., US

Syngas reformation into fuels is an attractive opportunity to diversify away from petroleum and address energy-dependency concerns. Rh and Co-based catalysts used within Fischer-Tropsch (FT) process selectively convert syngas into oxygenates and hydrocarbons respectively but [...]

In Situ Investigation of Uptake Phenomena of Biological Molecules and Silica Nanoparticles into Mammalian Cells in Microstructures

Lee W.G., Bang H., Yun H., Kim J.A., Cho K., Shin Y.S., Chung C., Chung N.C., Chung C., Chung N.C., Chang J.K., Han D-C, Seoul National University, KR

Electroporation is a powerful gene transfection method to deliver foreign biological molecules such as DNA and protein into living cells with electric pulsations. However, conventional cuvette-type electroporation techniques generally suffer from poor transfection efficiency and [...]

Active Sealing for Soft Poymer Microchips

Bang H., Lee J., Lee W.G., Park J., Yun H., Lee J., Lee W.G., Chung C., Chung S., Cho K., Chung C., Chung S., Han D-C, Chang J.K., Seoul National University, KR

This paper presents a universal sealing method for soft polymer (elastomer) microchips. A robust and reversible sealing method which allows various materials to be bonded and sealed tightly with each other even in aqueous solutions, [...]

Amphiphilic Self-assembled Nanoparticles Composed of Chitosan and Ursolic Acid for Protein Delivery on the Skin

Lee S.B., Cho K., Shim J.K., Korea Institute of Industrial Technology, KR

Several promising studies have been reported for the protein delivery such as cytokines using nano-sized particles, which have detrimental effect on the loading the protein without localization and releasing it without deactivation. To design the [...]

Highly Efficient Electro-permeabilization of Mammalian Cells Using Micro-electroporation Chip

Shin Y.S., Kim J.K., Lim S.H., Lee Y., Lee Y.K., Cho K., Lee Y., Lee Y.K., Chung C., Chung S., Chung C., Chung S., Han D-C, Chang J.K., Seoul National University, KR

Electroporation, is widely used method that can be directly applied to the field of gene therapy. However, very little is known about the basic mechanisms of DNA transfer and cell response to the electric pulse. [...]

Nanopatterning of Periodically Strained Surfaces – A Kinetic Monte Carlo Simulation Study

Larsson M.I., Sabiryanov R.F., Cho K., Clemens B.M., Stanford University, US

We present kinetic Monte Carlo simulations of nanopatterning by using strain-assisted nucleation of adatom islands on periodically strained fcc(111) surfaces. The goal of our work is to predict conditions and limitations for producing nanopatterns. It [...]