UA – TechConnect Briefs

Enhancement of anticancer action of traditional (doxorubicin and cisplatin) and experimental (landomycin A) drugs by their delivery in vivo with novel C60-fullerene-based nanocarriers possessing innate ROS-modulating activity

Panchuk R., Prylutska S., Skorokhyd N., Lehka L., Skivka L., Hurmach V., Evstigneev M., Piosik J., Berger W., Prylutskyy Yu., Scharff P., Stoika R., Vari S., Institute of Cell Biology NAS of Ukraine, UA

Rapid development of multi-drug resistance of tumor cells to chemotherapy caused by the over-expression of specific ABC-transporter proteins and/or multiple defects in genes involved in cell cycle and apoptosis regulation in cancer cells frequently leads [...]

Conjugation of anticancer drugs with novel PEG-containing nanocarrier provides circumvention of drug-resistance mechanisms in vitro and protects of general toxicity in vivo

Kоbylinska L., Panchuk R., Skorohyd N., Senkiv Y., Heffeter P., Berger W., Boiko N., Mitina N., Zaichenko A., Lesyk R., Zіmenkovsky B., Stoika R., Vari G.S., Danylo Halytsky Lviv National Medical University, UA

In the last decade, the development of targeted drug delivery with conjugated nanoparticles brings more drug molecules to the diseased sites, at the same time reducing a systemic drug exposure. Polyethylene glycol (PEG) conjugation is [...]

Neuroactive Carbon Dots: Perspective Neurotheranostic Agents and Harmful Environmental Pollutant

Borisova T., Dekaliuk M., Pozdnyakova N., Pastukhov A., Dudarenko M., Galkin M., Borysov A., Vari S.G., Demchenko A.P., Palladin Institiute of Biochemistry NAS of Ukraine;, UA

1 Palladin Institute of Biochemistry, NAS of Ukraine – RECOOP CRRC 2 International Research and Innovation in Medicine Program, Cedars-Sinai Medical Center, LA, CA, USA Carbon dots (C-dots) are a newly discovered class of fluorescent [...]

Hydrophilic NaYF4 nanocrystals doped with Eu3+: Effects of surface functionalization on glutamate and GABA transport in brain nerve terminals

Borisova T., Sojka B., Kociołek D., Banski M., Pozdnyakova N., Pastukhov A., Borysov A., Galkin M., Dudarenko M., Podhorodecki A., Palladin Institiute of Biochemistry NAS of Ukraine;, UA

Hydrophilic NaYF4 nanocrystals doped with Eu3+: Effects of surface functionalization on glutamate and GABA transport in brain nerve terminals T. Borisova2, B.Sojka1, D.Kociołek1, M. Banski1, N. Pozdnyakova2, A. Pastukhov2, A.Borysov2, M. Galkin2, M. Dudarenko2, A. [...]

Thermoelectric properties of molecular nanostructures

Kruchinin S.P., Bogolyubov Institute for Theoretical Physics, UA

We use the concept of resonant tunneling to calculate the thermopower of molecular nanosystems. It turns out that the sign of the thermovoltage under resonant tunneling conditions depends sensitively on the participating molecular orbital, and [...]

Application Magnetite of Nanoparticles (ICNB Preparation) as Magnetically-Resonant Contrasting Means During Visualization of Tumours

Belousov A.N., Laboratory of Applied Nanotechnology Belousova A.N., UA

In investigation on animals (Vistar rats) was proof that magnetite of nanoparticles (ICNB) are contrast means for malignant tumour visualization. Was been shown that magnetite of nanoparticles have contrast effect when performing magnetic resonance imaging [...]

Thermoelectric properties of molecular nanostructures

Kruchinin S.P., Bogolyubov Institute for Theoretical Physics, UA

We use the concept of resonant tunneling to calculate the thermopower of molecular nanosystems. It turns out that the sign of the thermovoltage under resonant tunneling conditions depends sensitively on the participating molecular orbital, and [...]

Application Magnetite of Nanoparticles (ICNB Preparation) as Magnetically-Resonant Contrasting Means During Visualization of Tumours

Belousov A.N., Laboratory of Applied Nanotechnology Belousova A.N., UA

In investigation on animals (Vistar rats) was proof that magnetite of nanoparticles (ICNB) are contrast means for malignant tumour visualization. Was been shown that magnetite of nanoparticles have contrast effect when performing magnetic resonance imaging [...]

Why not only electrostatic discharge but even a minimum charge on the surface of highly sensitive explosives can catalyze their gradual exothermic decomposition and how a cloud of unipolar charged explosive particles turns into ball lightning

Meshcheryakov O., Wing Ltd Company, UA

Even a single excess electron or ion migrating on the surface of sensitive explosives can catalyze their gradual exothermic decomposition. Mechanisms underlying such a charge-induced gradual thermal decomposition of highly sensitive explosives can be different. [...]

Novel Immune Biosensors Based on the Structured Nano-Porous Silicon for Control of Mycotoxins in Environmental Objects

Starodub N.F., Slishek N.F., Pylypenko I.V., Pylypenko L.N., Pylypenko I.V., Pylypenko L.N., National University of Life and Environmental Sciences of Ukraine, UA

To meet all the requirements of practice in respect of high sensitivity of analysis of mycotoxins as well as simplicity, cheapness and rapidity of its currying out we propose to use of structured nano-porous silicon [...]