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In Vivo Tracking of Liposomes Using CT and MR Imaging

Zheng J., Liu J., Jaffray D.A., Allen C., University of Toronto, CA
Currently, there are limited methods available for longitudinal and non-invasive in vivo assessment of the transport kinetics of carrier-based therapeutics, such as those relying on liposomes. A viable strategy to non-invasively track the carrier in [...]

Direct-Write CMOS-Based Laboratory-On-Chip

Ghafar-Zadeh E., Sawan M., Therriault D., École Polytechnique de Montréal, CA
Over the recent years, the identification of genes which influence many diseases has been highly demanded and now, molecular diagnosis is most promising technology to offer fast and early detection of diseases to a maximum [...]

Surface modification and characterization of a cyclic olefin copolymer for magnetic bead-based stop-flow microfluidic ELISA

Herrmann M., Veres T., Tabrizian M., McGill University, CA
This abstract describes a microfluidic platform for simple, highly effective and parallel Enzyme Linked Immuno-Sorbent Assay (ELISA). The method is based on the use of magnetic micro-beads in order to increase the capture rate of [...]

PCR-free DNA-based biosensing with polymeric optical hybridization transduction using micro- and submicron-magnetic bead captured on micro-electromagnetic traps

Dubus S., Le Droggof B., Gravel J-F., Boudreau D., Veres T., Laval University, CA
DNA-based biosensor technologies for rapid, sensitive and affordable identification of genetic material are in constant evolution and show great potential in various fields. The ability for such methods to be used directly at point-of-care settings [...]

Rapid Detection of Multiple Myeloma using a microfluidic platform

Kaigala G., VanDjinkin J., Taylor B.J., Backhouse C.J., Pilarski L.M., University of Alberta, CA
MM has a unique molecular signature and is well suited as a model system for performing analysis on microchips. MM multiplex genetic analysis for clonotypic signatures and genetic abnormalities offers the possibility for genetic profiling [...]

Nano Clinical Challenges: Policy options

Power C., University of Alberta, CA
Nanotechnology has been utilized to embellish and accelerate genetic testing via technologies like the “lab-on-a-chip. The incremental shift from micro to nano will be indicative of the direction of development with many of these innovations. [...]

Nanostructured perovskite-based oxidation catalysts for improved environmental emission control

Seegopaul P., Bassir M., Alamdari H., Van Neste A., Nanox Inc., CA
The emission control catalyst market is about $11 billion and growing while global concerns over environmental pollution have resulted in increasingly stringent regulations. This business opportunity, however, is complicated by the requirement for higher performance [...]

Gold Composite- and Macroporous Gold Nanoparticle Films by a Vertical Deposition Method

Badilescu S., Kahrizi M., Ashrit P.V., Truong V-V, Concordia University, CA
Composite films have been prepared in one step by a vertical deposition method from the aqueous suspension of gold colloids and polystyrene (PS) microspheres. The composite is formed on a glass substrate by convective assembly [...]

RF Noise Models of MOSFETs- A Review

Asgaran S., Jamal Deen M., McMaster University, CA
A thorough study of high frequency MOSFET noise compact modeling with emphasis on channel thermal noise modeling is presented. Although the modeling of MOSFET noise dates back to many years ago, the enhanced noise generated [...]

The Effects of the Gate Tunneling Current on the High Frequency Noise Parameters of MOSFETs

Deen J., Ranuárez J.C., Chen C-H, McMaster University, CA
The impact of the gate tunneling current (GTC) on the noise performance of MOSFETs with very thin gate oxides is studied by developing analytical expressions for the four parameters that describe the noise performance of [...]

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