BE – Page 4 – TechConnect Briefs

Stable Self-Assembled Monolayers for sensitive biosensor interfaces

Jans H., Jans K., Jans H., Jans K., Bonroy K., Frederix F., Reekmans G., Maes G., Borghs G., IMEC, BE

One of the most important requirements for making advanced biosensors and biochips is the attachment of biological receptors onto a solid support. For this reason, it is important to construct a stable and well-characterized interface [...]

Shape-controlled synthesis and functionalization of gold nanoparticles for hyperthermia applications

Van de Broek B., Frederix F., Bonroy K., Jans H., Maes G., Borghs G., IMEC, BE

Control of nanoparticle shape may initially seem like a scientific curiosity, but its goal goes far beyond aesthetic appeal. The shape not only influences the chemical and optical properties of metal nanoparticles, but also their [...]

Lab-on-chip for the isolation and characterization of circulating tumor cells

Laureyn W., Liu C., O’Sullivan C.K., Llaudet E., Nilsson O., Drese K.S., Roeser T., Ritzi M., Hauch S., Albert W., Borgen E., Nygren A.O.H., IMEC, BE

A consortium of 7 European partners has undertaken the challenging task to develop a microfluidic system (μTAS) capable of the isolation/enrichment and consecutive RNA/DNA characterization of circulating tumor cells (CTCs), to be used as a [...]

Simulations of the Anchor Losses in MEM Disk Resonators

Paci D., Stoffels S., Tilmans H.A.C., IMEC, BE

MEM (Micro Electro Mechanical) resonators have been proposed as fundamental components in RF transmission systems; especially bulk mode resonators are very attractive devices because of their small size and their high resonance frequencies combined with [...]

Correlation of Experimental and Numerical Results on Electrostatically Actuated Micro-Beams

Rochus V., Rixen D.J., Golinval J.-C., University of Liege, BE

The aim of this paper is to validate numerical simulations of electromechanical coupling in micro-structures using some experimental results. The micro-structures studied here consist in a micro-bridge and two cantilever beams. Multi-physics simulations of micro-electro-mechanical [...]

Influence of the Casimir force on the static and dynamic behavior of electrostatically driven micromechanical resonators

Stoffels S., Fernández L.J., Puers R., Tilmans H.A.C., IMEC, BE

Nowadays, electrostatically driven high frequency micromechanical resonators are being developed in which the gap spacing is minimized in order to achieve sufficiently high electromechanical coupling. Typical gap spacings for resonators operated close to a GHz [...]

Industrial Applications of Nano-Track Etched Templates and Films

Hanot H., Ferain E., Legras R., it4ip, BE

It4ip is a supplier of state-of the-art research and Hi-Tech products based on the combination of ion-track technology of polymers with template capability to make high value added nano-objects, nano-structures and smart membranes.rnrnThe range of [...]

Construction of High-performance Biosensor Interface through Solvent Controlled Self-assembly of PEG grafted Polymer

Zhou C., keersmaecker K.De, Braeken D., Reekmans G., Bartic C., De Smedt H., Engelborghs Y., Borghs G., Interuniversity Microelectronics Center (IMEC), BE

The ability to control biomolecular interactions at the solid-liquid interface is essential for the development of high-performance biosensors. Conventional methods to tailor the surface properties of biosensors are based on Self-Assembled Monolayers (SAMs) and Surface [...]

Development of a Novel Triblock Copolymer Therapeutic Nanoreactor

Ranquin A., De Vocht C., Meier W., Steyaert J., Van Gelder P., VUB, BE

Currently chemotherapy is one of the major strategies to treat cancer patients. It is however limited by several drawbacks such as low bioavailability of chemotoxins, low drug concentrations at the tumor site, systemic toxicity, lack [...]

On Chip Induced Phagocytosis for Improved Neuronal Cell Adhesion

Van Meerbergen B., Raemaekers T., Winters K., Braeken D., Bartic C., Engelborghs Y., Annaert W., Borghs G., IMEC, BE

Efficient integration of neuronal cells and electronic devices could result in hybrid bi-directional communication systems that would enable us to interact at fundamental level with biological structures and get insight in the mechanisms governing their [...]