The isolation and analysis of circulating tumor cells (CTCs) from blood is the subject of intense research. Tests to detect metastasis are available but progress is hampered by the lack of tumor-specific markers and predictable [...]
Breast cancer is the most common cause of cancer death in women; more than 75 % of patients die from skeletal metastases. The accurate diagnosis of metastatic disease is therefore crucial for treatment and survival. [...]
CytImmune Sciences is developing colloidal gold nanoparticles (cAu) as a platform for tumor targeted drug delivery. Specifically two drugs are discussed: Aurimune-T and AuriTax. Aurimune-T is manufactured by covalently linking molecules of TNF and Thiol-derivatized [...]
The efficacy of current cancer chemotherapy is mainly limited by toxicity associated with the systemic spread of anticancer drugs to normal tissues. Enhancing selectivity or maximizing targeting towards cancer cells would be important approach to [...]
Chemotaxis plays a key role in cancer metastasis, directing the motility of metastatic cells through gradients of growth factors or other chemoattractants. In order to rigorously characterize the role of growth factors in cancer cell [...]
Catalase mimics can be used as therapeutic agents against oxidative stress in treatment of many diseases including Alzheimer’s disease, stroke, heart disease, aging and cancer. (Salen)Mn(III) compounds have been proven to be promising as synthetic [...]
There are numerous studies in the field that explain and model the behavior and heating properties of magnetic nanoparticles (NPs) when exposed to an alternating magnetic field [1, 2]. Particularly for applications such as magnetic [...]
By means of nanotechnological approach different coating procedures enlarging biocompatibility factors of implants were developed. The well-known materials – titanium plates are used as substrates supporting structures. Depending on the construction type (stable or rolling) [...]
The methods of site-specific delivery of antitumor agents without the general and system consecuences remain to be actual because the need to reduce the negative effects of antitumor treatment. In the experiment attempts are made [...]
, Korsunska N.E.
, Zhukov P.
, Zhukov T.
, Ostapenko S.
, Sellers T.
, Zajac A.
, Zhukov P.
, Zhukov T.
, University of South Florida, US
Ovarian cancer is the most lethal gynecologic malignancy. This largely reflects the fact that approximately 75% of cases are detected at advanced stages of disease, when cure is unlikely. In contrast, 5-year survival for patients [...]
Recent development of nanoparticle technology and its application in hyperthermia therapies makes it possible to consider optimal control of the temperature field and thermal energy delivered to the tumor region with minimal destruction of surrounding [...]
Carbon nanotubes (CNTs) are remarkable solid state nanomaterials due to their unique properties such as high surface area, hollow cavities, and excellent mechanical and electrical properties. Interfacing carbon nanotubes with biological materials could enable significant [...]
Journal: TechConnect Briefs
Volume: 1, Technical Proceedings of the 2005 NSTI Nanotechnology Conference and Trade Show, Volume 1
Published: May 8, 2005
Industry sectors: Advanced Materials & Manufacturing | Medical & Biotech
Topics: Biomaterials, Cancer Nanotechnology