Papers – Page 15 – TechConnect Briefs

Three-Dimensional Single Step Flow Sheathing in Micro Cell Sorters

Goranovic G., Perch-Nielsen I., Larsen U.D., Wolff A., Kutter J., Telleman P., Bio/Chemical MicroSystems, DK

We present a novel microstructure that enables 3 dimensional hydrodynamic focusing of cells in a pressure driven micro cell sorter. This so-called "chimney" structure for single step coaxial sheathing was designed and optimized through simulation, [...]

A Fluid Dynamics Model for a Plasma Ion Acceleration System

Domingo F.S., Ramos H.J., University of the Philippines, PH

We present preliminary results of some simulations for a plasma ion acceleration system, which we plan to construct. This system tires to model the complex interactions between the multiple species of ions (about 5) used [...]

Computational Design Analysis for In-Plane Microfluidic Valves

Dickey C.K., Makhijani V.B., Deshmukh A., Liepmann D., CFD Research Corporation, US

Simulations of fluid flow across in-plane microvalves were performed using an advanced multi-physics commercial software system and compared with experimental data. Model validation required careful consideration of leakage pathways left by fabrication artifacts. Following model [...]

A Mathematical Model of a Biosensor

Botkin N.D., Schlensog M., Tewes M., Turova V.L., Center of Advanced European Studies and Research, DE

A mathematical model of a biosensor is considered. The biosensor is supposed to be used for the measurement of small amounts of certain substances in liquids. The device works as follows: acoustic shear waves are [...]

Application of the Direct Simulation Monte Carlo Method to Modeling of Microfluidics

Sharipov F., Universidade Federal do Parana, BR

For mathematical modeling of microfluidics it is necessary to calculate a rarefied gas flow through micropumps, microvalves and other elements with high accuracy. Since the size of microfluidics is close to the molecular mean free [...]

Simulation of Droplet Formation in Micromixers

Hardt S., Schönfeld F., Weise F., Hofmann C., Ehrfeld W., Institut für Mikrotechnik, DE

Droplet formation in micromixers developed by the Institute of Microtechnology Mainz (IMM) is investigated by methods of computational fluid dynamics (CFD). The CFD results are compared to experimental data obtained with transparent micromixers made from [...]

Modeling of Blood Flow in Simple Microchannels

Trebotich D., Chang W., Liepmann D., University of California-Berkeley, US

Optimal design of medical micro-assay systems will require computational modeling capabilities. Most existing models are based on macroscale experiments with smallest length dimensions comparable to that of a capillary due to the fact that the [...]

Electrodynamic Transport, Electroporation and Lysis of Cells in Pharmacological and Bioanalytical Microsystems

Przekwas A.J., Chen Z.J., Athavale M., CFD Research Corporation, US

Biological information is stored in cells and is the prime object of interest of pharmacological, biomedical, and bioanalytical professionals. Whatever the interest: elcectroporative drug delivery and pharmacodynamics, in vivo PCR, infection pathology, DN

Inverted Method for Simulation of Electrokinetic Transport in Microchannel Devices

Nilson R.H., Griffiths S.K., Sandia National Laboratories, US

An inverted method of solution is used to numerically solve the equations governing electrokinetic fluid flow and species transport in microscale turns, junctions and curved channels. Rather than solving for the electric potential and fluid [...]

Analysis of Sample Transport in Capillary Electrophoresis Microchip Using Full-Scale Numerical Analysis

Krishnamoorthy S., Feng J.J., Makhijani V.B., CFD Research Corporation, US

An implicit finite-volume numerical scheme has been developed to solve the three-dimensional transport equations along with fully-coupled ionization equilibria in acid/base systems. The scheme solves conservation equations for mass and momentum while satisfying the electroneutrality [...]