Biomaterials – Page 124 – TechConnect Briefs

Electrohydrodynamic Interactions of an AFM Tip and a Biological Membrane

Fan T.H., Fedorov A.G., Georgia Institute of Technology, US

In biological applications, AFM imaging needs to be performed in the natural (aqueous) living environment of the cell in order to observe molecular level interactions and biochemical processes in-situ in the electrolyte solution and to [...]

Bio Nano Systems and Chemistry

Modeling AFM Induced Mechanical Deformation of Living Cells

Rudd R.E., McElfresh M., Balhorn R., Allen M., Belak J., Lawrence Livermore National Laboratory, US

One challenge with using Atomic Force Microscopy (AFM) for recognition microscopy on living cells is the fact that the cell is not rigid, and as the force is applied to a receptor site, it is [...]

MEMS for Drug Screening Applications

Zhou J., Zurn S., Markus D., Mantell S.C., Polla D., Smith G., University of Minnesota, US

MEMs offer a quick, low cost method for screening new drugs. In this MEMs application, microbeams were designed such that an affinity between the beam surface (coated with a biomolecule) and a second biomolecule (simulating [...]

Electrically Triggered Hydrogels: Mathematical Models and Simulations

Chatterjee A.N., De S.K., Aluru N.R., University of Illinois, US

Environmentally sensitive hydrogels have enormous potential in various applications. Ionic polymer gels have been shown to respond to a number of different stimuli like pH and electric field. One of the major advantages of electro-responsive [...]

Modeling the Interaction between Bristle Elastic Structures and Fluids

Botkin N.D., Hoffmann K-H, Starovoitov V.N., Turova V.L., Center of Advanced European Studies and Research, DE

The interaction of a solid multi-layered structure with a fluid is studied. Such a problem arises when modeling HPSW sensors operating in liquids. The surface of HPSW biosensors is covered by specific receptors called aptamers. [...]

A Micro Cantilever-based Pathogen Detector

Weeks B.L., Camarero J., Noy A., Miller A.E., Stanker L., De Yoreo J.J., Lawrence Livermore National Laboratory, US

Increasing efforts have been put into the developments of cantilever-based micro sensors. These devices show fast responses, high sensitivity, and are suitable for mass production. Currently, they are mainly applied for quality and process control, [...]

Topic: Biomaterials