Medical & Biotech – Page 73 – TechConnect Briefs

Lessons learned from the field, how to protect yourself from occupational exposure to engineered nanomaterials

Hodson L.L., Geraci. M. Methner C.L., Crawford C., CDC/NIOSH, US

NIOSH has visited over 26 nanomaterial facilites, evaluated workplace exposures and created recommended guidance to reduce potential exposures to nanomaterials. A summary of lessons learned about effective control strategies will be shared.

Modeling Aggregation and Size Distribution of Nanoparticles with Monte Carlo Simulation

Liu H., Surawanvijit S., Rallo R., Orkoulas G., Cohen Y., University of California, Los Angeles, US

The size distribution of the nanoparticles and their aggregates is crucial for predictions of the fate and transport of nanoparticles in the environment. A computational model was developed in the present work based on a [...]

A Non-contact Co-Culture Model of Peripheral Neural Cells for Nanotoxicity, Tissue Engineering and Pathophysiological Studies

Jaiswal A., Wong Y.Y.W., Bhushan A., Daniels C., Lai J.C.K., Idaho State University, US

Cell culture models in vitro have long served as tools for the elucidation of pathophysioligcal cellular and molecular mechanisms of diseases. Recently these versatile model systems have permeated into toxicology and tissue engineering research. Although [...]

The Use of Nanoscale Zero Valent Iron for Environmental Remediation – Benefits and Possible Pitfalls

Chan-Remillard S., Borda M., Crawford A., Kloschinsky T., Stenroos P., Marques L., Goudey J.S., HydroQual Ltd and Golder Associates Ltd/Inc., CA

Nanoscale zero valent iron (nZVI) is the primary nanoscale particle that is being used for environmental remediation of contaminated groundwater and soils. Golder Associates Ltd. and HydroQual Laboratories (a wholly owned subsidiary of Golder) has [...]

Functional polymer hydrogels for water purification applications

Liu Y., State University of New York at Stony Brook, US

Filtration is necessary in many engineering field. Polymeric membranes have been used in filtration application for more than a decade. However, some of the contaminants, e.g. radiounuclides and toxic metals, present in soluble form in [...]

Environment, Health & Safety

Polyethylene-oxide (PEO) linear nano-polymer directly stimulates endothelium and protects myocardium from focal ischemia-reperfusion injury via eNOS pathway in rats

Uryash A., Arias J., Wu H., Adams J.A., Mount Sinai Medical Center, US

Medical grade Nano-polymers (NP) used to enhance circulation, drug and gene delivery. Injection of Polyethylene-oxide (PEO) increase tissue perfusion and decrease mean blood pressure in animal models. Polyethylene-oxide (PEO) NP’s ultra high molecular weight (2-5 [...]

Leveraging Ontologies for Improved Medical Outcomes Assessment: Implementing Medical Management Technology to Drive Innovation

Little E., CTG Life Sciences, US

Sensor data - such as that produced by many kinds of nanotechnologies - can be difficult to manage and maintain. This is especially true in areas of biomedicine where contextual information is important to capture [...]

Computational Modeling of Electromagnetically Induced Heating of Magnetic Nanoparticle Materials for Hyperthermic Cancer Treatment

Rast L., Harrison J.G., University of Alabama at Birmingham, US

We present results on the computational modeling of electromagnetically induced heating for the purpose of hyperthermic cancer treatment with magnetic nanoparticle fluids. Magnetic hyperthermia can therefore be used for direct targeting and destruction of tumors [...]

Determination of the Electroporation Threshold for pulses from 95 ns to 20 us

Saulis G., Balevicius S., Saule R., Stankevic V., Zurauskiene N., Vytautas Magnus University, LT

The dependences of the fraction of electroporated mouse hepatoma MH-22A cells on the pulse intensity were obtained for the cells exposed to single square-wave electric pulses with the durations from 95 ns to 20 us. [...]