Medical & Biotech – Page 41 – TechConnect Briefs

Biocompatible Nanotubes as potential Nanocarriers for hydrophobic model food and drug bioactives

Sadeghi R., Kalbasi A., Moosavi-Movahedi A.A., Emam-Jomeh Z., Razavi S.H., Karimi M., Kokini J., University of Illinois at Urbana-Champaign, US

Biocompatible nanotubes (NTs) have great potential applications especially in food and drug delivery. The NTs are very interesting because they have uniform wall thickness, two open ends, different interior and exterior layers, different size and [...]

2D Engineering of Protein-Based Nanoparticles for cell guidance

Tatkiewicz W.I., Seras-Franzoso J., García-Fruitós E., Vazquez E., Ventosa N., Ratera I., Villaverde A., Veciana J., Institut Ciencia Materials de Barcelona (CSIC)/CIBER-BBN, ES

Cells responses, like positioning, morphological changes, proliferation and apoptosis, are the result of complex chemical, topographical and biological stimuli. Here we show the macroscopic responses of cells when nanoscale profiles made with Inclusion Bodies (IBs) [...]

Preparation of BSA Nanoparticles by desolvation method as a delivery system for nutraceuticals

Sadeghi R., Kalbasi A., Moosavi-Movahedi A.A., Karimi M., Kokini J., University of Illinois at Urbana-Champaign, US

The production of biocompatible nanoparticles (NPs) is one the most attractive research areas in food and drug sciences. The more the ratio of desolvating agents the bigger the particles size. The best ratio for ethanol, [...]

A novel mechanism for the synthesis of ultra-purified silver nanoparticles for the use in biomedical materials

Zuniga P., Chaves J.S., Chaves S.J., Chaves J.S., Chaves S.J., Universidad de Costa Rica and Instituto Tecnologico de Costa Rica, CR

Biomedical products are regulated by high standards of purity and quality compared to those that are not going to be linked to the human body. So it is a real challenge to incorporate a nanotechnological [...]

Chitosan-based nanomaterials for drug delivery and antibiotic-free bacterial control

Vila-Sanjurjo C., Fuenzalida J.P., Menchicchi B., Coelho D., Engwer C., Hoffman S., Pereira S., Remuñán-López C., Alonso M.J., Vidal A., Moerschbacher B., Kollenbrock S., Fetzner S., Philipp B., Goycoolea F.M., Westfaelische Wilhelms Universitaet - Muenster, DE

Research focused on chitosan (CS)-based nanostructured materials has burgeoned in the past decade or so, particularly in the biosciences and bionanotechnology fields. Chitosan characteristics (Mw and degree of acetylation), as well as the processing conditions [...]

Effects of CdTe QDs on protein structural changes

Ma X., Liang X., Liu L., Hu X., Fan J., Northwest University, CN

The nano-scale material, quantum dots (QDs), has been widely used in biological labels, imaging of fixed cells and tissues due to their excellent properties, such as small size, large surface area, good photostability, and negligible [...]

A Specific Surface-coating Peptide for Rare Earth Nanomaterials

Zhang Y.J., Zhou W., Wen L.P., University of Science and Technology of China, CN

The induction of autophagy on exposure of cells to a variety of nanoparticles represents both a safety concern and an application niche for engineered nanomaterials. Using phage display, we have discovered an 11-amino acid peptide [...]

Multi-functionalizations of Mesoporous Hollow Silica Nanospheres and Their HIFU Application

Chen H., Chen Y., Zhang K., Wang X., Chen H., Chen Y., Shi J., Shanghai Institute of Ceramics, CN

High intensity focused ultrasound (HIFU), as a representative non-invasive therapeutic mode, has attracted extensive attentions among biological and medical researchers. In this report, we focused on constructing novel mesoporous hollow silica nanospheres (MHSNs) as innovative [...]

Large-scale manufacturing of radiation sculptured therapeutic nanogels

Dispenza C., Grimaldi N., Sabatino M.-A., Adamo G., Rigogliuso S., Ghersi G., Università di Palermo, IT

Pulsed electron-beam irradiation of poly(N-vinyl pyrrolidone) (PVP) aqueous solutions, at relatively low energy per pulse and doses within the sterilization dose range, has led to a variety of PVP nanogels of controlled size, that can [...]

Investigations on Transmembrane Ion Channels Suspended over Porous Silicon Membranes

Tantawi K.H., Berdiev B., Cerro R., Williams J.D., University of Alabama in Huntsville, US

This article presents a batch-fabricated porous silicon membrane tool used to investigate transmembrane protein functionality in complex biological systems. We address the physical and chemical requirements fabricate the thin porous membrane, attached a lipid bilayer, [...]