Medical & Biotech – Page 133 – TechConnect Briefs

A Micromachined Sparse Cell Isolation Device: Application in Prenatal Diagnostics

Mohamed H., Turner J.N., Caggana M., Wadsworth Center, New York State Department of Health, US

The isolation of fetal cells from maternal circulation is the subject of intense research. Fetal cells can be isolated using several enrichment methods, however no technique to specifically isolate and use them for genetic diagnosis [...]

Synthesis of Shear Thickening Fluid Using Sonochemical Method

Rangari V.K., Hassan T.A., Mahfuz H., Jeelani S., Tuskegee University, US

Shear thickening fluid is developed using sonochemical method which one step process and can be processed from its dry metal oxide powder forms instead of its colloidal solution. The main problem with the current process [...]

Microfluidics and Rheology of Carbon Black Dilute Suspensions: Modeling, Measurement, and Applications

Aramphongphun C., Hemminger O., Castro J.M., Lee L.J., The Ohio State University, US

Rheology and microfluidics are essential and challenging topics in designing microfluidic devices and materials processing. A study of rheological properties (e.g. viscosity) of complex fluids becomes more important in the flow at microscale due to [...]

Microfluidic System for Assessing the Controllability of MC-1 Magnetotactic Bacteria as Carriers in Micro-channels

Lu Z., Martel S., NanoRobotics Laboratory, CA

A novel micromanipulation method using Magnetotactic Bacteria to push micro-objects is proposed. The controllability of MC-1 Magnetotactic Bacteria in micro-channels is verified through microfluidic device with implemented micro-electromagets. After introducation of microfabrication procedure and experiment [...]

DNA Extraction with Parallel Electrodes on Microfluidic System

Parng S.H., Shia T.K., Yang H.J., Kuo C.H., Microsystem Technology Common Laboratory, TW

DNA trapping was demonstrated between an electrical field across two parallel integrated electrodes on chip fabricated by the MEMS techniques. The method to release the trapped DNA molecules using reversed voltage control electrical field was [...]

Computational Heat Transfer and Two-phase Flow in Miniature Tubes

Lakehal D., Narayanan C., ASCOMP, CH

We will report on our recent advances made in predicting this class of flow, using the Level Set approach, in which we have incorporated phase-change capabilities, surface tension and triple-line dynamics models based on the [...]

Experimental Visualization of Bubble Generation and Breakup in T-junctions of Microchannels

Zhang Y., Xiao Q., Cheng L., Wang L., The University of Hong Kong, HK

experimental visualization, bubble generation and breakup, T-junctions, microchannels

Microfluidic Device for Conventional and Traveling-Wave Dielectrophoresis

Kumar A., Acrivos A., Khusid B., James C.D., New Jersey Institute of Technology, US

Conventional and traveling-wave dielectrophoresis in suspensions are proven techniques for the manipulation, separation, and characterization of suspended particles with potential applications ranging from biological warfare agent detection to healthcare industry. In contrast to previous studies, [...]

Shape Oscillation and Internal Mixing in Sessile Liquid Drops using ElectroWetting-On-Dielectric (EWOD)

Miraghaie R., Sterling J.D., Nadim A., Keck Graduate Institute, US

We show that internal mixing within a sessile liquid drop can be significantly enhanced by means of so-called electrowetting-on-dielectric (EWOD), using an alternating electric potential. This is done experimentally by comparing the coalescence and mixing [...]

High-Throughput Screening Devices Based on Hydrophobic Microfluidics

Chen J.J., Yang H.J., Wu J.W., Parng S.H., Yu T.M., Industrial Technology Research Institute, TW

In this work, we developed a microfluidic assay for determination of the individual cell’s response to chemical exposure. Microfluidic chips comprisd four channels were fabricated on polystyrene (PS) substrates via mechanical milling processes, and covered [...]