Abbasi S., Arghya P., Afshan K., Prakash S.
McGill University, CA
Keywords: biodegradable, breast cancer, nanoparticles, siRNA
Polyethylenimine (PEI)-coated human serum albumin (HSA) nanoparticles form suitable biocompatible carriers for therapeutic molecules. Small interfering RNA (siRNA) molecules have suggested great promise as a future therapy for breast cancer. In order to overcome the problems of degradation and low cellular transfection associated with siRNA, PEI-HSA nanoparticles are used. These nanoparticles are characterized to allow efficient delivery of siRNA to MCF-7 breast cancer cells.
Journal: TechConnect Briefs
Volume: 1, Nanotechnology 2011: Advanced Materials, CNTs, Particles, Films and Composites
Published: June 13, 2011
Pages: 74 - 76
Industry sector: Advanced Materials & Manufacturing
Topic: Materials Characterization & Imaging
ISBN: 978-1-4398-7142-3