Reverse Thermoresponsive Polymers for Sustained Delivery of Therapeutic Agents

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CSIRO has developed thermoresponsive polymers for encapsulation and sustianed release of bioactives. They are stable aqueous solutions over 24 months, easily pass through a 25 gauge needle at room temperature and immediately gel into a sustained release depot on in vivo injection. They are designed to be biodegradable and well tolerated in vivo based. Theyare able to deliver therapeutic agents, enzymes/proteins and small molecule drugs over an extended period of time. Additionally, the materials and their components are compendia materials and amenable to existing GMP manufacture.

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Journal: TechConnect Briefs
Volume: 3, Nanotechnology 2013: Bio Sensors, Instruments, Medical, Environment and Energy (Volume 3)
Published: May 12, 2013
Pages: 278 - 280
Industry sectors: Advanced Materials & Manufacturing | Medical & Biotech
Topics: Biomaterials, Materials for Drug & Gene Delivery
ISBN: 978-1-4822-0586-2