Papers – Page 875 – TechConnect Briefs

Formation of Nanoparticles of a Hydrophilic Drug using Supercritical CO2 and Microencapsulation for Sustained Drug Release

Thote A.J., Gupta R.B., Auburn University, US

The problem of initial burst release, in sustained drug delivery devices was resolved by reducing the active pharmaceutical ingredient particle size by using Supercritical Antisolvent technique with Enhanced Mass-transfer (SAS-EM)., Encapsulation was performed using a [...]

Peptidic Nanoparticles for Cancer Therapy and Diagnosis

Graff A., Tropel D., Raman SK., Machaidze G., Lustig A., Burkhard P., University of Basel, CH

Somatostatin peptides such as somatostatin 28 or 14 are known for their high binding affinity to G-coupled peptide receptors, which are often over-expressed on tumor cells. Using this binding property we developed a new type [...]

Liquid Crystal Interactions with Nanostructure and Applications to Diagnostics and Medical Research

Israel B.A., Murphy C.J., Abbott N.L., Platypus Technologies, US

We will present data demonstrating the use of liquid crystal detection of protein in the development of rapid, label free diagnostics and assays. We control the orientation of liquid crystals by the fabrication of surfaces [...]

Nanoelectronic CO2 Breath Sensors

Star A., Joshi V., Thomas D., Niemann J., Gabriel J.-C.P., Valcke C., Nanomix Inc, US

The measurement of carbon dioxide levels in respiration is a standard of care or guideline according to the American Heart Association, the American Association of Respiratory Care, and the American Society of Anesthesiologists, and is [...]

Plasma-Treated and Collagen-Coated PLLA Nanofiber Membrane for Cartilage Tissue Engineering

Chen J.P., Lee S.F., Chiang I.P., Chang Gung University, TW

Biodegradable nanofiber membranes from poly-L-lactic acid (PLLA) were prepared by electrospinning to be used as a scaffold in cartilage tissue engineering. Parameters during the electrospinning process were studied in detail in terms of diameters of [...]

Static Magnetic Field Effects on Cells: A Possible Road to Cell Differentiation

Prina-Mello A., Campbell V., Coey J.M.D., Trinity College, IE

The use of higher uniform magnetic field intensity, such as those used in magnetic resonance imaging, is thought to exert little influence at the cellular level. There are several experimental studies that indicate that magnetic [...]

Effect of Microtopography and Cell Concentration on T Lymphoid Cell Migration during in vitro Extravasation Process

Prina-Mello A., Volkov Y., Prendergast P.J., Trinity College, IE

The locomotion of leukocyte cells has been proved to be influenced by microtopographical patterns with and without surface chemistry [Prina-Mello et al., 2003, Lo et al., 2000]. In this study, parallel grooves were microfabricated on [...]

Transient Analysis of Cooling of Biological Tissues Using Semi-Infinite Approximation

Jain A., Rensselaer Polytechnic Institute, US

In the present paper, we have presented an analytical approach for transient analysis of cooling of biological tissues due to blood flow. Semi-infinite approximation for tissues is used and continuum approach is used for modeling.

TMAZ Nanoparticles as Potential Drugs Influencing the Cellular Signal Transduction Pathways

Ivkovic S., Baranek T., Bendzko P., Schulz J., Klinomed Institut für Angewandte Nanotechnologie und Nanomedizin GmbH, DE

Currently, various antioxidants are under clinical investigation as an adjunct to standard and experimental cancer therapies. Anti-cancer activity of antioxidants may not only be attributed to their radical scavenger properties, but also to direct modulation [...]

Nanomagnetic Immunoassay for Rapid Detection of Escherichia coli

Haik Y., Qablan A., Chen C-J., Center for Nanomagnetics and Biotechnology, US

This study identifies a simple process to quickly conduct an analysis, under field conditions, for detection of pathogens. A magnetic sandwich immunoassay is developed for rapid isolation and detection of targeted pathogen. Escherichia coli BL21 [...]