Papers – Page 629 – TechConnect Briefs

Adsorption kinetics of bacteria onto a thin Fe3O4 magnetic nanofilm

Ansari F., Aref A., Libor S., Horvath R., Ramsden J.J., Cranfield University, UK

A range of bacteria have been shown to be able to remove sulfur from organic compounds that commonly exist in petroleum. The most extensively investigated microorganisms belong to the genus Rhodococcus, which has shown reasonably [...]

Cytotoxicity of bare and PEGylated silica nanoparticles as potential gene-delivery vectors

Yagüe C., Saldaña L., Martin F., Arruebo M., Vilaboa N., Santamaria J., Universidad fe Zaragoza, ES

Silica and other inorganic carriers are one of the major groups used to transport drugs and bioactive molecules into cells. The others are viral carriers, organic cationic compounds and recombinant proteins. The use of mesoporous [...]

A Needs-based Assessment of Measurements for Nanotechnology / Environmental Health and Safety

Allocca C.M., Campbell T., National Institute of Standards and Technology, US

The National Institute of Standards and Technology (NIST) is engaged in a continuing needs-based assessment of the state of the United States Measurement System (USMS). The USMS assessment addresses innovation-limiting measurement needs in three ways: [...]

Gold nanoparticle-based miniaturized NSET Probe for rapid and ultra-sensitive detection of toxic metals in soil, water and fish

Ray A., Ray P.C., Darbha G.K., Ray A., Ray P.C., Jackson State University, US

Contamination of the environment with toxic metals like mercury and arsenic have been an important concern throughout the world for decades. Human exposure to high Hg or As levels can harm the brain, heart, kidneys, [...]

Modulation of g-Irradiation Induced ROS Responses by Engineered Fullerenes in Human Epidermal Keratinocytes

Gao J., Wang H.-L., Shreve A.P., Iyer R., Los Alamos National Laboratory, US

High-dose ionizing irradiations can cause acute tissue and organ damage, especially severe cutaneous lesions. These cutaneous injuries often result in further complications and incur high mortality. Therefore, it is critical to develop effective therapeutic approaches [...]

Spatio-temporal Tumor Model for Analysis and Mechanism of action of Intracellular Drug Accumulation

Mishra S., Katiyar V.K., Arora V., Haridwar, IN

We have developed a one-dimensional tumor simulator to describe the biodistribution of chemotherapeutic drugs to a tumoral lesion and the tumor cell’s response to therapy. A three-compartment model is used for drug dynamics within the [...]

Upconverting nanoparticles for photodynamic therapy

Chatterjee D.K., Zhang Y., National University of Singapore, SG

Photodynamic therapy involves killing of diseased cells by excitation of photosensitizer chemicals with high energy light to produce cytotoxic oxygen species from surrounding dissolved oxygen. However, poor tissue penetration of high energy light and hydrophobic [...]

Pharmacokinetic study of PEGylated plasmon resonant gold nanoparticles in tumor-bearing mice

Kogan B.Ya., Andronova N.V., Khlebtsov B.N., Khlebtsov N.G., Khlebtsov B.N., Khlebtsov N.G., Rudoy V.M., Dement’eva O.V., Sedykh E.M., Bannykh L.N., FGUP “GNC “NIOPIK”, RU

Gold nanorods and gold nanoshells have been synthesized. Nanorods have length of 50 nm, diameter of 15-20 nm. Nanoshells have 80 nm silica core diameter with 25 nm thick gold shells. Then poly(ethylene glycol) molecules [...]

Bacterial Drug Delivery Systems and nanoparticles

Sharma R., Haik Y., UNCG, US

Multi- Walled Carbon Nanotubes Increase the Efficiency of Hyperthermic Chemotherapy

Levi-Polyachenko N.H., Merkel E., Jones B.T., Wagner W.D., Carroll D.L., Stewart IV J.H., Wake Forest University Health Sciences, US

A clinically applied method to enhance drug localization for abdominal malignancies of colorectal cancer involves a two-hour perfusion of hyperthermic (40-42ºC) chemotherapeutic agents; however, all cavity tissues are subjected to enhanced drug delivery due to [...]