Microwave irradiation and Click chemistry for highly efficient and chemoselective multivalent iron oxide nanoparticle surface modification

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Magnetic nanoparticles (mNPs) are attractive candidates for numerous applications due to their unique properties. For all these applications mNPs surfaces must be tailored to improve biocompatibility properties or reduce aggregation but also to insert molecules on the particles with precise control of their architecture and surface density. So new methodologies for controlled and efficient functionalization of such materials are needed. In this contribution we will describe the use of various chemical approaches (microwave, click chemistry, photochemistry) for mNPs functionalization and present results of improve grafting rates (up to 40 fold increase). We moreover will propose a new nanoplateform allowing an orthogonal and chemoselective double functionalization.

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Journal: TechConnect Briefs
Volume: 1, Nanotechnology 2013: Advanced Materials, CNTs, Particles, Films and Composites (Volume 1)
Published: May 12, 2013
Pages: 416 - 419
Industry sector: Advanced Materials & Manufacturing
Topics: Nanoparticle Synthesis & Applications
ISBN: 978-1-4822-0581-7