Teker K., Sivakumar K., Wickstrom E., Panchapakesan B.
University of Delaware, US
Keywords: antibodies, confocal microscopy., electronic sensing, HER2, nanotube field effect transistors
Carbon nanotubes (CNTs) are remarkable solid state nanomaterials due to their unique properties such as high surface area, hollow cavities, and excellent mechanical and electrical properties. Interfacing carbon nanotubes with biological materials could enable significant advances in biomedical applications such as disease diagnosis and treatment. In addition, the bioconjugated nanotubes combine with the sensitive nanotube-based electronic devices would enable sensitive biosensors toward medical diagnostics. This paper presents electronic sensing of antibodies that are specific to HER2 surface receptors in cancer cells with nanotube field effect transistor devices. This paper also presents antibody functionalization of carbon nanotubes and its potential applications for breast cancer diagnostics.
Journal: TechConnect Briefs
Volume: 1, Technical Proceedings of the 2005 NSTI Nanotechnology Conference and Trade Show, Volume 1
Published: May 8, 2005
Pages: 43 - 46
Industry sectors: Advanced Materials & Manufacturing | Medical & Biotech
Topics: Biomaterials, Cancer Nanotechnology
ISBN: 0-9767985-0-6