Mattu C., Sartori S., Ranzato E., Boffito M., Li R., Ciardelli G.
Politecnico di Torino, IT
Keywords: nanoparticles, Paclitaxel, polyesters, polyurethanes
Biodegradable polymeric micro and nanoparticles have shown to be promising forms for the delivery of a wide array of drug formulations, such as hydrophobic or hydrophilic active principles, proteins or other bio molecules. The aim of this study was to prepare micro and nanospheres starting from commercial polyesters, such as Poly-ε-Caprolactone (PCL) and Poly Lactic Acid (PLA) or proprietary polyester-urethanes (PU), for the controlled and targeted delivery of the anticancer drug Paclitaxel (PX) which has proved high efficacy against different tumours.
Journal: TechConnect Briefs
Volume: 3, Nanotechnology 2011: Bio Sensors, Instruments, Medical, Environment and Energy
Published: June 13, 2011
Pages: 314 - 317
Industry sectors: Advanced Materials & Manufacturing | Medical & Biotech
Topics: Biomaterials, Materials for Drug & Gene Delivery
ISBN: 978-1-4398-7138-6