Using intra chemiluminescent resonance energy transfer (CRET) between DNA aptamer and fluorescein and physical property of graphene sheet, cost-effective and simple biosensor was developed for the rapid quantification of Hg2+ in a sample. The limit of detection (LOD = background + 3) for the biosensor with extremely low background, due to the removal of free DNA aptamer using graphene sheet, was compared with those of conventional analytical methods capable of quantifying Hg2+. The accuracy, precision, and recovery of highly sensitive biosensor were excellent within acceptable error range.
Journal: TechConnect Briefs
Volume: 1, Advanced Materials: TechConnect Briefs 2015
Published: June 14, 2015
Pages: 152 - 154
Industry sector: Advanced Materials & Manufacturing
Topics: Carbon Nano Structures & Devices