Application of chemiluminescent resonance energy transfer and graphene sheet for the rapid quantification of mercury in a sample

Kim Y.T.; Kwon M.; Lee J-H.; Lee S-Y; Park Y.

Application of chemiluminescent resonance energy transfer and graphene sheet for the rapid quantification of mercury in a sample

Kwon M., Park Y., Lee J-H., Lee S-Y, Kim Y.T., Lee J-H., Lee S-Y
Luminescent MD, LLC, US

Keywords: aptamer, chemiluminescence resonance energy transfer (CRET), graphene sheet, mercury

Using intra chemiluminescent resonance energy transfer (CRET) between DNA aptamer and fluorescein and physical property of graphene sheet, cost-effective and simple biosensor was developed for the rapid quantification of Hg2+ in a sample. The limit of detection (LOD = background + 3) for the biosensor with extremely low background, due to the removal of free DNA aptamer using graphene sheet, was compared with those of conventional analytical methods capable of quantifying Hg2+. The accuracy, precision, and recovery of highly sensitive biosensor were excellent within acceptable error range.

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Journal: TechConnect Briefs
Volume: 1, Advanced Materials: TechConnect Briefs 2015
Published: June 14, 2015
Pages: 152 - 154
Industry sector: Advanced Materials & Manufacturing
Topic: Carbon Nano Structures & Devices
ISBN: 978-1-4987-4727-1