stent – TechConnect Briefs

Bioabsorbable Anti-inflammatory Material: A Novel Protein-Conjugated Polymer with Applications in the Implantable Medical Device Field

Rapier C.E., Chen E., Liu W.F., Lee A.P., University of California Irvine, US

Biodegradable/bioabsorbable materials are a relatively new movement in the implantable medical device field. Despite the promise of non-permanent implants, bioabsorbable materials can induce a localized inflammatory immune response. To overcome this limitation, we are combining [...]

Nanoscale tailoring of the surface properties of biomedical devices by layer-by-layer technique

Chiono V., Carmagnola I., Boccafoschi F., Gentile P., Tonda-Turo C., Del Pilar Camacho Leal M., Ballarini M., Ciardelli G., Politecnico di Torino, IT

The layer-by-layer (LbL) technique is a versatile solvent-free process allowing the coating of surfaces with uniform ultrathin multilayered films to tailor surface properties and structure at the nanoscale. LbL approach is a promising tool to [...]

A lattice Boltzmann study of the non-Newtonian blood flow in stented aneurysm

Kim Y.H., Farhat S., Lee J.S., Wayne State University, US

The treatment of cerebral aneurysms with a minimally invasive porous stent has recently been proposed to prevent rupture and favor coagulation mechanism inside the aneurysm. But, an irregularly shaped and wide-necked aneurysm makes current stent [...]

Gene Delivery and Transfection Studies with Lipopolyplexes in Human Endothelial and Smooth Muscle Cells

Brito L., Little S., Langer R., Amiji M., Northeastern University, US

Non-viral gene delivery and transfection in primary human vascular endothelial cells (EC) and smooth muscle cells (SMC) has tremendous potential for cardiovascular diseases, such as in treatment of coronary restenosis. Using a combination of synthetic [...]