silica nanoparticles – Page 2 – TechConnect Briefs

Effect of Silica Nanoparticles on Rheological Properties and Gelation Temperature of Biodegradable Polymer Gels

Florián-Algarín V., Acevedo A., University of Puerto Rico-Mayagüez, PR

The discovery of new potent and insoluble drugs has emphasized the need for personalized dosages and novel drug-delivery systems. The use of biodegradable polymers is a good alternative to form films in which a solid [...]

Differential Uptake of PEG-Silica-FITC Nanoparticles by Human Breast Cancer Cells and Normal Human Breast Epithelial Cells

Iwakuma N., Sharma P., Delano M.J., Moldawer L.L., Moudgil B.M., Grobmyer S.R., University of Florida, US

Background: An understanding of uptake of nanoparticles (NPs) by human cancer cells and non-cancer cells is important for the development of NPs as novel cancer therapeutic and diagnostic agents. Hypothesis: Uptake of NPs is increased [...]

In Situ Investigation of Uptake Phenomena of Biological Molecules and Silica Nanoparticles into Mammalian Cells in Microstructures

Lee W.G., Bang H., Yun H., Kim J.A., Cho K., Shin Y.S., Chung C., Chung N.C., Chung C., Chung N.C., Chang J.K., Han D-C, Seoul National University, KR

Electroporation is a powerful gene transfection method to deliver foreign biological molecules such as DNA and protein into living cells with electric pulsations. However, conventional cuvette-type electroporation techniques generally suffer from poor transfection efficiency and [...]