PSA – TechConnect Briefs

Detection of Prostate-Specific Antigen (PSA) with an Ultra High Performance Electrode Modified with Sol-Gel Au Nanoparticles

Leung S.W., Mozneb S., Lai J.C.K., Assan D., Idaho State University, US

Prostate cancer is one of the leading cancer causing death in men, especially in western developed countries. Prostate-specific antigen (PSA) is one of the biomarker that can be used to diagnose prostate cancer, although using [...]

Photosensitive Biosensor Array Chips not having the Addressing Circuit

Ahn C-G, Ah C.S., Ahn C-G, Kim A., Kim T., Park C.W., Yang J.H., Kim A., Kim T., Sung G.Y., Electronics and Telecommunications Research Institute, KR

This paper presents photosensitive biosensor array chips with the simple photodiode array having the optical input signal and the electrical output signal, which detects the photocurrent change caused by a reaction between probe molecules and [...]

Biochip-Based Test System for Cancer Diagnostics. Simultaneous Quantitation of Total and Free Forms of Prostate-Specific Antigen

Osipova T., Sokolova Z., Ryabykh T., Karaseva V., Modorsky M., Matveev V., Baryshnikov A., N.N. Blokhin Cancer Research Center, RAMS, RU

Background. Prostate-specific antigen (PSA) is the most useful marker for the early detection of prostate cancer (PCa). The use of two PSA forms – total (PSAt) and free (PSAf) makes it possible to differentiate benign [...]

Label-Free Protein Nano-Biosensor Using Top-Down Fabrication

Ah C.S., Ahn C-G, Kim A., Yu H.Y., Ahn C-G, Yang J.H., Baek I-B, Park C.W., Jun M.S., Lee S.J., Electronics and Telecommunications Research Institute (ETRI), KR

A nanosensor of n-type Si field-effect transistor (FET) via “top-down method” was employed to monitor PSA with great selectivity and high sensitivity up to 10 pg/mL. When a biomaterial, negatively charged PSA, is introduced through [...]