protein adsorption – TechConnect Briefs

Use of Inert CVD Coating for Protein, Corrosion, and Moisture Resistance in Bioanalysis Applications

Patterson L., SilcoTek Corporation, US

The desire to enhance the surface properties of base materials is especially prevalent in life science applications [1]. In order to keep up with evolving patient needs and clinical innovations, manufacturers in the medical industry [...]

Understanding How Nanopatterning Affects Protein Deposition

Casey B.J., Silverstein J.S., Kofinas P., Dair B.J., U.S. Food and Drug Administration, US

This work focuses on understanding the effects that nanotopology has on protein adsorption. Functionalized block copolymers were synthesized and processed to produced highly ordered, nanopattered films. Experiments utilizing a quart crystal microbalance were completed to [...]

Construction of High-performance Biosensor Interface through Solvent Controlled Self-assembly of PEG grafted Polymer

Zhou C., keersmaecker K.De, Braeken D., Reekmans G., Bartic C., De Smedt H., Engelborghs Y., Borghs G., Interuniversity Microelectronics Center (IMEC), BE

The ability to control biomolecular interactions at the solid-liquid interface is essential for the development of high-performance biosensors. Conventional methods to tailor the surface properties of biosensors are based on Self-Assembled Monolayers (SAMs) and Surface [...]

A Behavior of Protein Adsorption on Poly(Ethylene Glycol)-Modified Surfaces under Flow Conditions at Relatively Low Concentrations for Microfluidics Systems

Chun C-J, Lenghaus K., Riedel L., Bhalkikar A., Hickman J.J., University of Central Florida, US

Microfabrication technology has been used to create new microfluidics systems for bioanalytical and medical device applications in the last decade. The handling of relatively small amounts of analytes, at significantly lower concentrations, combined with the [...]