phage – TechConnect Briefs

Optimization of Phage-Based Magnetoelastic Biosensor Performance

Huang S., Yang H., Johnson M., Wan J., Chen I., Petrenko V.A., Chin B.A., Auburn University, US

A magnetoelastic (ME) platform coated with a bio-molecular recognition element (bacteriophage) for selective and specific recognition of Bacillus anthracis spores is described. ME materials have a mass-sensitive, characteristic, resonant frequency. In response to the binding [...]

Optimization of Phage-Based Magnetoelastic Biosensor Performance

Huang S., Yang H., Johnson M., Wan J., Chen I., Petrenko V.A., Chin B.A., Auburn University, US

A magnetoelastic (ME) platform coated with a bio-molecular recognition element (bacteriophage) for selective and specific recognition of Bacillus anthracis spores is described. ME materials have a mass-sensitive, characteristic, resonant frequency. In response to the binding [...]

Evolutionary selection of bone mineral hydroxyapatite binding peptide using landscape phage library

Modali S., Abbineni G., Jayanna P., Petrenko V., Mao C., University of Oklahoma, US

Hydroxyapatite [(Ca5(PO4)3OH)2] is a biomineral which is associated with bone proteins to form mineralized extracellular matrix in a mature bone. Using two landscape phage libraries, in which random octa-peptides and nona-peptides are displayed on all [...]

Engineering hybrid nanostructures with phage particles

Makowski L., Chen L., Argonne National Laboratory, US

Assembling complex structures comprising multiple, inorganic functional elements represents a significant engineering challenge. We have constructed hybrid nanostructures based on T7 and M13 phage and incorporating a variety of metals and metal oxides. Synthesis of [...]

Simultaneous Detection of Salmonella typhimurium and Bacillus anthracis Spores Using Phage-Based Magnetoelastic Biosensors

Huang S., Yang H., Johnson M., Chen I., Petrenko V.A., Chin B.A., Auburn University, US

Deliberate contamination of the food supply has become a concern, Salmonella typhimurium and Bacillus anthracis spores being primary pathogens of interest. The objective of this research was to investigate simultaneous detection of these two biological [...]