pH-sensitive – TechConnect Briefs

Nano Graphene Oxide as Drug Carrier for Antihypertensive Agent: Benazepril, Captopril and Losartan

Wang J., Long Y., Tao C., Liu H., Zhu H., Zhou X., National University of Defense Technology, CN

Graphene oxide (GO) offers large surface and novel biocompatible properties that are currently being explored for advanced drug carriers. GO has a one-atom-thick two dimensional carbon system, which contains several kinds of oxygen functional groups [...]

Study on the novel drug vehicle with multimodal imaging function

Wu P.J., Liu T.Y., Institute of Biomedical Engineering, National Yang-Ming University of Taiwan (ROC), TW

Recently, in order to combine diagnosis with therapy in a single box, drug delivery systems (DDSs) associating with imaging functions were developed to improve the efficacy of diseases detection, delivery of therapeutic agents, and the [...]

Action of Paclitaxel pH-Sensitive Liposomes on B16F1 Melanoma Cells

Karanth H., Murthy R.S.R., The M.S. University of Baroda, IN

Long circulating pH-sensitive liposomes loaded with Paclitaxel were developed and characterized for the encapsulation efficiency, release characteristics and its action on B16F1 melanoma cells (low metastatic). Paclitaxel loaded pH-sensitive liposomes showed better release pattern and [...]

pH-Sensitive Nano-Crystals of Carbonate Apatite Regulate Delivery and Release Kinetics of DNA for Efficient Expression in Mammalian Cells

Chowdhury E.H., Akaike T., Tokyo Institute of Technology, JP

The completion of whole human genome sequencing encourages the development of a powerful gene delivery technology for elucidating structure, regulation and function of genes and proteins in addition to the emerging biomedical applications, such as [...]