PET – TechConnect Briefs

Recycled PET Nanofibers Produced by Electrospinning Technique

Gomes S.S., Oliveira A.M., Maia A., Zanin M.H.A., Institute for Technological Research, Group for BioNanoManufacturing, BR

The universe of science and materials technology has been revolutionized with the development of materials at nanoscale, which contribute to the improvement of material properties and development of new materials, such as non-woven recycled polyethylene [...]

Imaging the Distribution of High Colloidal Stability Mesoporous Silica Nanoparticles (MSNs) with PET and MRI

Laprise-Pelletier M., Bridot J.-L., Guillet-Nicolas R., Lagueux J., Gossuin Y., Laurent S., Vander Elst L., Kleitz F., Fortin M.-A., Université Laval, CA

Biocompatible and high porosity mesoporous silica nanoparticles (MSNs) represent a significant advance in drug delivery applications, currently entering clinical validation. It will be necessary to track these drug vectors over time with medical imaging techniques. [...]

Computational Studies on Mechanisms for the Organocatalytic Depolymerization of Poly(ethylene) Terephthalate

Jones G.O., Horn H.W., Wei D.S., Fukushima K., Lecuyer J.M., Coady D.J., Hedrick J.L., Rice J.E., IBM, US

Poly(ethylene) terephthalate (PET) is a widely used thermoplastic commonly found in packaging products and that constitutes a large percentage of total plastic refuse. We have examined the depolymerization of PET with alcohols and amines, a [...]

Computational Studies on Mechanisms for the Organocatalytic Depolymerization of Poly(ethylene) Terephthalate

Jones G.O., Horn H.W., Wei D.S., Fukushima K., Lecuyer J.M., Coady D.J., Hedrick J.L., Rice J.E., IBM, US

Poly(ethylene) terephthalate (PET) is a widely used thermoplastic commonly found in packaging products and that constitutes a large percentage of total plastic refuse. We have examined the depolymerization of PET with alcohols and amines, a [...]

Flexible Graphene Transistors via Printing Transfer

Chang T.-C., Suh H.-S., Mikael S., Seo J.-H., Nealey P.F., Ma Z., University of Wisconsin-Madison, US

Graphene is an atomic layer material with the characteristics of high mobility, high mechanical strength, transparency and low injection energy barrier with different work function metals. Good transparent electrodes and flexible graphene-based large scale touch [...]

Imprint Lithography-Based, Multimodal Contrast Agents and the Effect of Shape and Size on Biodistribution

Herlihy K.P., Merkel T.J., DeSimone J.M., UNC Chapel Hill, US

Polymer research and modern medicine are at a critical juncture. Many state of the art, small molecule therapeutics are difficult to deliver effectively because of poor solubility and rapid elimination by the reticuloendothelial system. In [...]

Radiolabeling of Nanoshells with Cu-64 and In-111 for PET and SPECT Imaging in Rats

Xie H., Wang Z., Bao A., Goins B., Phillips W.T., Coleman C.L., Texas Southern University, US

Here we report for the first time the radioactive labeling of gold-silica nanoshells with Cu-64 and In-111. A bifunctional polyethylene glycol (PEG2000) is used as crosslinker to connect nanoshells with DOTA or DTPA, which are [...]

Effects of the Shape of Nanoparticles on the Crystallization Behavior of Poly(ethylene terephthalate) Nanocomposites in the Flow Fields

Kim B.C., Jang K.H., Hahm W.G., Kikutani T., Lee J., Hanyang University, KR

This paper investigated the effects of the shape of nanoparticles on the crystallization behavior of high molecular weight poly(ethylene terephthalate) (PET ; inherent viscosity of 0.98 g/dl) in the shear and elongational flow fields. Two [...]

Automated Microfluidic Chip and System for the Synthesis of Radiopharmaceuticals on Human-Dose Scales

van Dam R.M., Elizarov A.M., Ball E., Shen C.K-F, Kolb H., Rolland J., Diener L., Williams D., Edgecombe B., Stephen T., Heath J.R., Siemens Molecular Imaging Biomarker Research, US

We present a fully-automated microfluidic system for the multi-step chemical synthesis of radiopharmaceuticals such as radiolabeled probes for positron emission tomography (PET). In earlier work, we developed a proof-of-principle PDMS microfluidic chip with a coin-shaped [...]

Coin-Shaped Reactor in Microfluidic Devices Used for Radiopharmaceutical Synthesis

Elizarov A.M., Kolb H.C., van Dam R.M., Heath J.R., Padgett H.C., Huang J., Daridon A., California Institute of Technology, US

A microfluidic device designed and optimized for the multi-step synthesis of PET (Positron Emisssion Tomography) probes is presented. It is the first device in its class to produce radiopharmaceuticals of sufficient quality and quantity (over [...]