nanoparticle – Page 14 – TechConnect Briefs

Nanoscaled Mg(OH)2 Used as Flame Retardant Additive

Zhou B., Zhou Z., Wu Z., Fransson M., Zhou B., Zhou Z., Headwaters Technology Innovation LLC, US

Headwaters Technology Innovation (HTI) has applied aqueous colloidal chemistry with great success in the development of “bottom-up” nanomaterials and nanotechnologies. One such material is a nano-scaled magnesium hydroxide, NxCat® Mg(OH)2, which is primarily used as [...]

Assembly of Nanoscale Scaffolds from Peptide Nucleic Acids (PNA)

Husk Jr. T., Bergstrom D.E., Purdue University, US

Deoxyribonucleic acid or DNA has been demonstrated to be a useful scaffold for self-assembling nanomaterials. Peptide nucleic acids, or PNA, which retains the nucleic acid bases adenine, cytosine, guanine, and thymine on a pseudo-peptide backbone [...]

Fabrication of Nanoparticle Embedded Polymer Nanorod by Template Based Electrodeposition

Kang S-W, Kang W-S, Nam G-H, Kim H-S, Kim J.H., Kim K-J, Kim H-S, Kim J.H., Kim K-J, Kang S-W, Kang W-S, Kim H-S, Kim J.H., Kim K-J, Ajou University, KR

Inorganic semiconductor materials in nano-dimension have drawn intense attention in recent years because of their size-tunable optoelectronic properties arising from the quantum confinement effect. These materials often require to be incorporated into other materials, often [...]

Novel organic-inorganic nanohybrids based on poly(N,N-dimethyl acrylamide)-l-polyisobutylene amphiphilic polymer conetworks

Mezey P., Domján A., Iván B., Thomann R., Mülhaupt R., Hungarian Academy of Sciences, HU

Poly(N,N-dimethyl acrylamide)-l-polyisobutylene (PDMAAm-l-PIB) amphiphilic conetworks were synthesized. Thermal analysis (DSC), small angle X-ray scattering (SAXS) measurements and atomic force microscopy (AFM) investigations were made. Furthermore, we have successfully synthesized silver nanoparticles in the PDMAAm-l-PIB amphiphilic [...]

Redispersible hybrid nanopowders: cerium oxide nanoparticle complexes with phosphonated-peg oligomers

Qi L., Sehgal A., Castaing J.-C., Fresnais J., Berret J.-F., Chapel J.-P., Rhodia/CNRS joint Institution, US

Rare earth cerium oxide (ceria) nanoparticles are stabilized using end-functional phosphonated-PEG oligomers. The complexation process and structure of the resulting hybrid core-shell singlet nanocolloids are described, characterized and modeled using light and neutron scattering data. [...]

Evaluation of Nanoencapsulated DNA Vaccine for RSV

Boyoglu S., Vig K., Rangari V., Pillai S., Dennis V., Singh S.R., Alabama State University, US

Polymer nanoparticles have been used as carriers to enhance drug delivery. Among them chitosan is the most commonly used carrier, because it promotes long term of incorporated drugs. In the present study,we used DNA vaccine [...]

How much advantage do Nanoscale Phenomena afford for Pulmonary Delivery?

Walji N., Thanou M., Quirke N., Imperial College London, UK

Although claims of improved performance due to nanoscale phenomena are made on a daily basis, exactly how much advantage can be afforded by nanotechnology for specific medical applications is quantitatively unknown. It is generally suggested [...]

Gene Delivery and Transfection Studies with Lipopolyplexes in Human Endothelial and Smooth Muscle Cells

Brito L., Little S., Langer R., Amiji M., Northeastern University, US

Non-viral gene delivery and transfection in primary human vascular endothelial cells (EC) and smooth muscle cells (SMC) has tremendous potential for cardiovascular diseases, such as in treatment of coronary restenosis. Using a combination of synthetic [...]

Cell-mediated, heat-based therapy for combating HIV infection

Denver H.T., de Noronha C.M., Borca-Tasciuc D-A., Rensselaer Polytechnic Institute, US

There is an increased interest in developing alternative therapies to combat deadly infectious disease including HIV. This work investigates the fundamentals of a novel, nanoparticle-based potential treatment method employing macrophage cells. Macrophages are a very [...]

Multilayered ABCD Nanoparticles for siRNA delivery

Thanou M., Miller A., Imperial College London, UK

RNAi therapeutics represent a method to treat human diseases by addressing targets that are not possible to be addressed with conventional medicines. In our Centre we design nanosized systems for siRNA delivery that consist of [...]