mitochondria – TechConnect Briefs

Mitochondria-targeting Gold Nanoparticles for Improved Therapeutic Efficacy of Photodynamic Therapy of Breast Cancer

Yang Y., Gao N., Hu Y., Jia C., Du H., Wang H., Stevens Institute of Technology, US

Photodynamic therapy (PDT) is an emerging minimally invasive therapeutic modality for a variety of oncologic diseases. In recognition of their superior optical and surface plasmonic properties, gold nanoparticles (Au NPs) can be utilized as the [...]

On-Chip Ion-selective Microesensor for Evaluation of Mitochondrial Membrane Potential

Lim T.-S., Dávila A., Wallace D.C., Burke P., UC Irvine, US

The mitochondrial membrane potential is used to generate and regulate energy in living systems, driving the conversion of ADP to ATP, and controlling apoptosis, all central to human health and disease. Therefore, there is a [...]

BioMEMS for Mitochondriaa Medicine

Padmaraj D., Zagozdzon-Wosik W., Xie Lei-Ming, Pijanowka D., Miller J.H., Grabiec P., Wosik J., Zagozdzon-Wosik W., University of Houston, US

We designed and fabricated BioMEMS for applications in subcelullar level studies, more specifically for monitoring complementary parameters important in mitochondria medicine.BioMEMS were first simulated using COMSOL 3.4 and then fabricated as an SU-8 based microfluidic [...]