microchip – TechConnect Briefs

Plasmon enhanced silver quantum cluster fluorescence for biochemical applications

Bernard S., Kutter J.P., Mogensen K.B., Technical University of Denmark, DK

Silver quantum clusters (AgQCs) consisting of typically 4-10 atoms and known to be highly fluorescing in the visible wavelength range. Here, plasmon-enhanced silver quantum cluster fluorescence is employed for chemical sensing in a simple microfluidic [...]

Active Sealing for Soft Poymer Microchips

Bang H., Lee J., Lee W.G., Park J., Yun H., Lee J., Lee W.G., Chung C., Chung S., Cho K., Chung C., Chung S., Han D-C, Chang J.K., Seoul National University, KR

This paper presents a universal sealing method for soft polymer (elastomer) microchips. A robust and reversible sealing method which allows various materials to be bonded and sealed tightly with each other even in aqueous solutions, [...]

A Capillary Electrophoresis Chip for Rhodamine B and Inorganic Ion detection Utilizing Contactless Capacitance Detection

Liu W.L., Chen W.J., Hsieh S.H., Tsai T.K., National Pingtung University of Science and Technology, TW

A microfluidic channel and a contactless capacitance detector wereintegrated on a glass chip by a semiconductor manufacturing process forseparating and analyzing Rhodamine B and inorganic ion. The electrodes of thecapacitance detector were formed successively by [...]

Development of Microfluidic Device for Heterogeneous Immunoassay on Polystyrene Platform with Electroosmotic Control

Pribyl M., Snita D., Marek M., Institute of Chemical Technology Prague, CZ

We have developed a microfluidic device for heterogeneous immunoassay on the polystyrene platform. The wire-imprinting method has been chosen for the construction of microchannel structure of the chip. Immunoassay based on the interaction of fluorescently [...]

Development and Characterization of a 2-D microchip-based Protein separation system

Feng J.J., Olazábal V, Olivares J.A., Sundaram S., Krishnamoorthy S., Iyer S., Los Alamos National Laboratory, US

Traditional methods in proteomics have relied on gel-based separation of proteins followed by directed cleavage of these proteins and mass spectrometry to measure the products. The emphasis on reliable, high-throughput analyses has led to the [...]

Modeling of Joule Heating in Electrophoretic Separation Microchips

Wang Y., Lin Q., Hoburg J.F., Mukherjee T., Carnegie Mellon University, US

This paper presents a model for Joule heating induced analyte dispersion in electrophoretic separation channels with a rectangular cross section. The model is in closed form and captures the effect of cross-sectional geometry. Three-dimensional numerical [...]

Computer Simulations of Electrokinetic Mass Transport in Microfabricated Fluidic Devices

Ermakov S.V., Jacobson S.C., Ramsey J.M., Oak Ridge National Laboratory, US

A mathematical model and computer code for simulat-ing electrokinetic fluid and sample manipulations in micro-fabricated fluidic devices (microchips) are described. The model accounts for mass transport mechanisms such as electrophoretic migration, bulk fluid motion due [...]