Magnetic Particles – TechConnect Briefs

FIRMS: A Novel Technique for Magnetic Molecular Imaging

De Silva L., Hu Q., Wang Y., Xu S.-J., University of Houston, US

Molecular imaging usually employs a labeling technique, mainly optical labeling or magnetic labeling, to highlight target molecules. While optical labeling uses a wavelength parameter to achieve molecular specificity, there is no analogous parameter in magnetic [...]

In vitro biosensing based on magnetically induced motion of magnetic nanoparticles

Dangl A., Kokkinis G., Keplinger F., Giouroudi I., Vienna University of Technology, AT

A method for in-vitro detection of bioanalyte using conductive microstructures to accelerate magnetic nanoparticles (MAPs) in an integrated microfluidic system is presented. The fundamental idea behind the elaboration of such a biosensing system is that [...]

Motion of Magnetic Chains in a Vibrating Field

Li Y-H, Sheu S-T, Pai J-M, Chen C-Y, National Chiao Tung University, TW

In this work, we have carried out an intensive experimental study on the manipulations of micro magnetic particle chains under vibrating magnetic fields. The chain is firstly formed by a uniform directional field, and then [...]

Force Discrimination for Enhanced Biosensor Specificity of Micro-Retroreflector Assays

Knoop J.D., Kemper S.M., Sherlock T., Cacao E., Ruchhoeft P., Willson R.C., University of Houston, US

In nearly all diagnostic/bioanalytical methods other than mass spectrometry, what is actually detected is a label of some sort, and the sensitivity and simplicity of detection of this label limits assay performance. Non-specific interactions between [...]

A Microfluidic Mixer for Chaotic Mixing of Magnetic Particles

Zolgharni M., Azimi S.M., Bahmanyar M.R., Balachandran W., Brunel University, UK

Magnetic isolation of specific biological entities through utilizing super-paramagnetic micro-particles has been of great interest in both bench-top and microfluidic platforms. Since the magnetic particles and target entities are suspended in separate fluids, prior to [...]

A Lab-on-a-Chip using Magnetic Droplets

Lehmann U., Parashar V.K., Vandevyver C., Gijs M.A.M., EPFL, CH

We present a chip-based bio-analysis system using the two dimensional (2D) magnetic manipulation of microdroplets. The latter contain magnetic microparticles which serve as force mediators for the droplet actuation. In combination with a changeable field [...]

PCR-free DNA-based biosensing with polymeric optical hybridization transduction using micro- and submicron-magnetic bead captured on micro-electromagnetic traps

Dubus S., Le Droggof B., Gravel J-F., Boudreau D., Veres T., Laval University, CA

DNA-based biosensor technologies for rapid, sensitive and affordable identification of genetic material are in constant evolution and show great potential in various fields. The ability for such methods to be used directly at point-of-care settings [...]